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墨旱莲乙酸乙酯总提物对小鼠免疫功能的调节作用
引用本文:刘雪英,蒋永培,赵越平,汤海峰.墨旱莲乙酸乙酯总提物对小鼠免疫功能的调节作用[J].中药材,2000,23(7):407-409.
作者姓名:刘雪英  蒋永培  赵越平  汤海峰
作者单位:第四军医大学西京医院,西安,710032
摘    要:目的:研究墨埋莲乙酸乙酯总提物(EAEEP)对机体免疫功能的调节作用。方法:采用正常及腹腔注射氢化可的松工呈不磷酰胺所致免疫低下小鼠模型,观察EAEEP对非特异免疫、细胞免疫体免疫功能的影响。结果:EAEEP可显著降低正常小鼠的脾指数、血清溶血素水平,并可显著抑制机体迟发性变态反应(DTH),而对于免疫功能低下小鼠,则可显著提高以上指标。结论:EAEEP具有调节小鼠免疫功能的作用。

关 键 词:墨旱莲乙酸乙酯总提物  EAEEP  免疫功能
修稿时间:2000年3月6日

Effect of Ethyl Acetate Extract of Eclipta prostrata on Mice of Normal and Immunosupression
Liu Xueying,Jiang Yongpei,Zhao Yueping,Tang Haifeng.Effect of Ethyl Acetate Extract of Eclipta prostrata on Mice of Normal and Immunosupression[J].Jorunal of Chinese Medicinal Materials,2000,23(7):407-409.
Authors:Liu Xueying  Jiang Yongpei  Zhao Yueping  Tang Haifeng
Institution:Pharmaceutical Department, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032.
Abstract:Objective: The regulatory effects of ethyl acetate extract of Eclipta prostrata ( EAEEP) on immune function were studied.Methods:The experimental immunosuppressive mice models were induced by injection of cyclophosphamide or hydrocarti-sone.Results:The index of spleen in normal mice were decreased significantly. So was the level of hemolysin in serum, Delayed trpe hypersensitivity was also inhibited at the same condition. But EAEEP can increase all these indexes in immunosuppressive mice.Conclusion;EAEEP possesses obvious regulatory action on immune function in mice.
Keywords:Ethyl acetate extract of Eclipta prostrata  Nonspecific immunity  Humoral immunity  Celluar immunity
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