Persistent SIRS and acute fluid collections are associated with increased CT scanning in acute interstitial pancreatitis |
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Authors: | Ayesha Kamal Mahya Faghih Robert A. Moran Elham Afghani Amitasha Sinha Nasim Parsa |
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Affiliation: | Division of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, MD, USA |
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Abstract: | Background: The use of computed tomography (CT) in acute pancreatitis (AP) continues to increase in parallel with the increasing use of diagnostic imaging in clinical medicine.Aim: To determine the factors associated with obtaining >1 CT scan in acute interstitial pancreatitis (AIP).Methods: Demographic and clinical data of all adult patients admitted between 1/2010 and 1/2015 with AP (AP) were evaluated. Only patients with a CT severity index (CTSI)?≤?3 on a CT obtained within 48?h of presentation were included.Results: A total of 229 patients were included, of whom 206 (90%) had a single CT and 23 (10%) had >1 CT during the first week of hospitalization. Patients undergoing >1 CT had significantly higher rates of acute fluid collection (AFC), persistent SIRS, opioid use ≥4 days, and persistent organ failure compared to those undergoing 1 CT (p?.05 for all). On multivariable analysis, only persistent SIRS (OR?=?3.6, 95% CI 1.4–9.6, p?=?.01) and an AFC on initial CT (OR?=?3.5, 95% CI 1.4–9, p?=?.009) were independently associated with obtaining >1 CT.Conclusion: An AFC on initial CT and persistent SIRS are associated with increased CT imaging in AIP patients. However, these additional CT scans did not change clinical management. |
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Keywords: | Acute pancreatitis CT scans persistent SIRS acute fluid collection |
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