| 摘 要： | <正>Neuronal injury and neuroprotection:Ischemia and reperfusion injuries in neuronal cells such as acute ischemic stroke-represent the third leading cause of death in the world.Current therapeutic concepts mainly aim to re-establish cerebral blood flow within a time window of less than 3 hours with the goal of limiting secondary brain injury.Secondary brain injury of thepenumbradevelops exponentially,causing severe mental and physical disabilities.The resulting morbidity and mortality in patients of all ages leads to an enormous economic burden.Neurons are well-known to possess a limited potential to recover and regenerate their basic function once damaged.Therefore the protection and especially the therapy of neuronal injuries in cells and organ systems has emerged
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