北京市不同营养状况中学生胰岛素抵抗状况分析

目的了解不同营养状况青少年胰岛素抵抗状况,为早期预防胰岛素抵抗提供理论依据。方法在北京市东城区选择初中三年级学生935名,进行身体测量、空腹血糖和胰岛素抵抗指标的测定。结果体重正常、超重和肥胖中学生胰岛素抵抗指标FINS(空腹胰岛素),HOMA-IR(稳态模型胰岛素抵抗指数),IAI(胰岛素敏感性指数)差异均有统计学意义(P值均<0.05),FPG差异无统计学意义(P>0.05)。随着BMI(体质指数)的升高,FINS,HOMR-IA,IAI绝对值逐渐升高。结论青少年肥胖与胰岛素抵抗存在一定相关性。超重和肥胖青少年已经出现胰岛素抵抗的现象,应重视并积极防治。

Insulin Resistance of Middle School Students Under Different Nutrition Status in Beijing

Objective To study insulin resistance of adolescents under different nutrition status, and to provide evidence for early prevention of insulin resistance. Methods Altogether 935 middle school students were selected from Dongcheng District, Beijing. Physical examination was performed and serum glucose and insulin resistance indices were determined for all subjects. Results The levels of FINS, HOMA-IR and IAI were different among normal, overweight and obesity students (P<0.05),but no statistical significance was fund in FPG. There was an increasing tendency in insulin resistance indices such as FINS, HOMR-IA and IAI absolute value along with body mass index(BMI) increasing. Conclusion Obesity is relevant to insulin resistance in adolescent. There are insulin resistance carriers among overweight and obese adolescents. More attention should be paid to prevent and treat it.