2001-2007年浙江省三门县钩端螺旋体病监测分析

目的了解浙江省三门县钩端螺旋体（钩体）病疫情动态及健康人群对钩体的免疫水平。方法用显微镜凝集实验，对临床确诊病例、健康人群血清进行抗体测定；采集鼠、蛙和牛中段尿，进行病原体分离培养。结果健康人群血清检测587份，阳性60份，血清抗体阳性率10.22%；鼠阳性率0.07%，为黄疸出血群；捕获青蛙1400只，牛中段尿140份，未检出阳性标本。结论夏秋季节为高发季节，青壮年农民为重点人群；健康人群血清抗体阳性率与宿主动物带菌率不一致，应继续加强对宿主动物和人群的监测，注意菌群变动。

Surveillance of leptospirosis in Sanmen county,Zhejiang, 2001-2007

Objective To investigate the current status of leptospirosis epidemic and the immunity level of health population in Sanmen, and get the information for the control and prevention of leptospirosis. Methods The antibody to leptospirosis was detected for clinically confirmed patients and health people by micro-agglutination test （MAT） ; Rats, frogs and the samples of midstream tLrine of cattle were taken to isolate the pathogen. Results A total of 587 serum samples from health people were detected, and 60 were positive （ 10.22% ）. The positive rate in the rats was 0.07% （icterohemorrhagic form）. The result of the detection for the frogs （1400） and the samples of cattle midstream urine （140） were negative. Conclusion The incidence of leptospirosis is high in summer and autumn, and young/ middle-aged farmers are affected mostly. The serum antibody positive rate of health population is inconsistent with that of animal host. The surveillance in population and animal host should be strengthened.