| 心脏重量指数评价左心功能不全价值的研究 |
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| 引用本文： | 陈茂,范忠才,饶莉,邓珏琳,杨庆,黄德嘉. 心脏重量指数评价左心功能不全价值的研究[J]. 四川医学, 2005, 26(5): 483-484 |
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| 作者姓名： | 陈茂 范忠才 饶莉 邓珏琳 杨庆 黄德嘉 |
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| 作者单位： | 四川大学华西医院,四川,成都,610041;四川大学华西医院,四川,成都,610041;四川大学华西医院,四川,成都,610041;四川大学华西医院,四川,成都,610041;四川大学华西医院,四川,成都,610041;四川大学华西医院,四川,成都,610041 |
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| 基金项目： | 国家自然科学基金资助项目 (30 2 70 566) |
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| 摘 要： | 目的 慢性充血性心力衰竭时,研究心脏重量指数(heartweightindex ,HWI) (心脏重量/体重)能否用于左心功能不全程度的评价。方法 采用阿霉素[2mg/(kg·周)×8周]制成兔的慢性充血性心力衰竭模型。用心脏彩超测量左室射血分数(EF) ,并测定HWI。结果 阿霉素使EF明显下降。阿霉素组(75 .41±6.5 6) % ,健康对照组(81.5 7±4.65 ) % ,P =0 .0 3。阿霉素组HWI明显高于对照组(P =0 .0 0 2 ) ,HWI与EF呈负相关(r =-0 .41,P =0 .0 2 7)。结论 HWI是评价左心功能不全严重程度较有价值的指标。
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| 关 键 词： | 慢性充血性心力衰竭 心脏重量指数 左室射血分数 |
| 文章编号： | 1004-0501(2005)05-0483-02 |
| 修稿时间： | 2005-03-09 |
Evaluation of left ventricular failure by heart weight index |
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| Chen Mao,Fan Zhongcai,Rao Li,et al.. Evaluation of left ventricular failure by heart weight index[J]. Sichuan Medical Journal, 2005, 26(5): 483-484 |
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| Authors: | Chen Mao Fan Zhongcai Rao Li et al. |
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| Affiliation: | Chen Mao,Fan Zhongcai,Rao Li,et al.West Ch ina Hospital,Sichuan University,Chengdu,Sichuan,610041,China |
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| Abstract: | Objective To assess the value of heart weight index (HWI) in evaluating heart function in heart failure.Methods Japanese white ears rabbits were used as chronic heart failure models by intravenously injecting adriamycin.Ejection fraction (EF) and HWI were meassured.Results 12 weeks after first adriamycin injection,EF was significantly reduced (P=0.03).HWI,meanwhile,was higher in adriamycin group than health control group (P=0.002),as well as the correlation of HWI and EF was signifant (r= -0.41 ,P=0.027).Conclusion When evaluating left ventricular failure,HWI is a valuable parameter. [Key words] chronic heart failure;heart weight index;ejection fraction |
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| Keywords: | chronic heart failure heart weight index ejection fraction |
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