| 男性2型糖尿病患者血清E2、T 和SHBG的含量变化 |
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| 引用本文： | 徐魁.男性2型糖尿病患者血清E2、T 和SHBG的含量变化[J].咸宁医学院学报,2006,20(1):26-27. |
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| 作者姓名： | 徐魁 |
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| 作者单位： | 咸宁学院附属第一医院内科,湖北咸宁437100 |
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| 摘 要： | 目的探讨男性2型糖尿病患者血清总睾酮(T)、总雌二醇(E2)及性激素结合蛋白(SHBG)的变化.方法选取正常男性37例,2型糖尿病男性患者46例,采用酶联放射免疫法测定血清胰岛素、总T、总E2、SH-BG含量.结果男性2型糖尿病患者较正常对照组总T降低,总E2、SHBG升高.男性2型糖尿病患者总T、总E2、SHBG与空腹胰岛素、120分胰岛素之间无明显相关性.结论血清性激素是反映男性2型糖尿病患者代谢变化的较好指标之一.
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| 关 键 词： | 2型糖尿病 睾酮 雌二醇 性激素结合蛋白 |
| 文章编号： | 1008-0635(2006)01-0026-02 |
| 收稿时间： | 2005-09-26 |
| 修稿时间： | 2005年9月26日 |
The Levels of Serum Testosterone, Estradiol and Sex Hormone-binding Globulin in Male Patients with Type 2 Diabetes Mellitus |
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| XU Kui.The Levels of Serum Testosterone, Estradiol and Sex Hormone-binding Globulin in Male Patients with Type 2 Diabetes Mellitus[J].Journal of Xianning Medical College,2006,20(1):26-27. |
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| Authors: | XU Kui |
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| Institution: | Department of Internal Medicine, The First Affiliated Hospital of Xianning College, Xianning Hubei 437100, China |
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| Abstract: | Objective To investigate the levels of serum testosterone,estradiol and sex hormone-binding globulin in male patients type 2 diabetes mellitus.Methods 46 male patients with type 2 diabetes mellitus,and 37 normal males were investigated.Serum levels of testosterone(T),estradiol(E_2),sex hormone-binging globulin(SHBG) and insulin were determined at the same time by ELISA.Results Compared with controls,the level of serum testosterone were decreased,and serum estradiol ad sex hormone-binding globulin levels were increased in type 2 diabetic male.It was also showed that no significant relationship between insulin and T,E_2 or SHBG was found in male patients with type 2 diabetes mellitus.Conclusion The serum levels of T,E_2 and SHBG are the perfect index showing the metabolic changes in male paltieuts with type 2 diabetes mellitus. |
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| Keywords: | Type 2 diabetes mellitus Testosterone Estradiol Sex hormone-binging globulin |
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