| 脑膜癌病68例脑脊液细胞学分析 |
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| 引用本文： | 吴小妹,谭利民,肖波,杨欢,张宁,毕方方,梁静慧.脑膜癌病68例脑脊液细胞学分析[J].脑与神经疾病杂志,2009,17(1). |
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| 作者姓名： | 吴小妹 谭利民 肖波 杨欢 张宁 毕方方 梁静慧 |
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| 作者单位： | 1. 中南大学湘雅医院神经内科,长沙,410008
2. 中南大学湘雅附二医院神经内科 |
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| 摘 要： | 目的探讨脑脊液检查对诊断脑膜癌病的重要意义。方法对68例确证的脑膜癌病患者临床资料进行回顾性分析。结果本组患者主要临床表现为头痛、恶心呕吐,脑膜刺激征等;仅15例患者的头部MRI增强扫描显示脑膜异常强化;脑脊液压力均增高,细胞数增多45例,常呈中-重度增加,并以激活型单核细胞增加为主,68例患者在脑脊液中均发现肿瘤细胞。结论脑膜癌病的临床表现及影像学缺乏特异性,脑脊液检查尤其是细胞学检查是诊断该病的可靠依据,而进行多次脑脊液细胞学检查可提高诊断准确率。
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| 关 键 词： | 脑膜癌病 脑脊液 细胞学 |
Cytological features of CSF in 68 patients with meningeal carcinomatosis |
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| WU Xiao-mei,TAN Li-min,XIAO Bo,YANG Huan,ZHANG Ning,BI Fang-fang,LIANG Jing-hui.Cytological features of CSF in 68 patients with meningeal carcinomatosis[J].Journal of Brain and Nervous Diseases,2009,17(1). |
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| Authors: | WU Xiao-mei TAN Li-min XIAO Bo YANG Huan ZHANG Ning BI Fang-fang LIANG Jing-hui |
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| Institution: | WU Xiao-mei,TAN Li-min,XIAO Bo,YANG Huan,ZHANG Ning,BI Fang-fang,LIANG Jing-hui. Neurology department of Xiangya Hospital,Central South University,Changsha 410008,China |
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| Abstract: | Objective To investigate the value of cerebrospinal fluid(CSF) examinations in diagnosing meningeal carcinomatosis. Methods The clinical data in 68 patients with meningeal carcinomatosis were analyzes retrospectively. Results The clinical menifestations of 68 patients were characterized by headache ,nausea and vomit ,meningeal irritation sign. MRI enhancement scanning found abnomally mater enhancement only in 15 cases. Cerebrospinal pressure increased in all cases.Cell population of CSF in moderate-severe d... |
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| Keywords: | meningeal carcinomatosis cerebrospinal fluid cytology |
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