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| Tween-80对鱼腥草注射液及鱼腥草挥发油的影响 | |
| 引用本文： | 谭志高,巢志茂,隋宇,刘海萍,吴晓毅,孙健,闫寒.Tween-80对鱼腥草注射液及鱼腥草挥发油的影响[J].中国中药杂志,2011,36(2):175-179. |
| 作者姓名： | 谭志高 巢志茂 隋宇 刘海萍 吴晓毅 孙健 闫寒 |
| 作者单位： | 1. 中国中医科学院,医学实验中心,北京,100700;中国中医科学院中药研究所,北京,100700 2. 中国中医科学院,医学实验中心,北京,100700 3. 中国中医科学院,中药研究所,北京,100700 |
| 基金项目： | 留学回国人员科技活动择优项目(国中医药研2006LHR06) |
| 摘 要： | 目的:研究聚氧乙烯脱水山梨醇单油酸酯(吐温80)对鱼腥草挥发油和鱼腥草注射液的影响.方法:重点针对醛基化合物和新生成的物质.从不同产地药材、不同贮存温度、不同贮存时间的角度,对鱼腥草挥发油、鱼腥草注射液、吐温80与鱼腥草挥发油的混合溶液进行1H-NMR的测定和谱图比较.结果:4个产地鱼腥草的挥发油均存在3个醛基的1H-NMR单峰,但在与吐温80混合后这些醛基峰基本消失,并在δ8.30处出现了新的1H-NMR峰.鱼腥草注射液在醛基吸收区域未见明显的1H-NMR峰,但在δ8.30处有微弱的1H-NMR峰,该δ 8.30峰在鱼腥草注射液于40℃恒温放置1到3个月后峰面积显著升高;结论:吐温80会使鱼腥草挥发油中的醛基类化合物含量显著降低并生成新的物质,鱼腥草注射液中含有微量的该新物质,并在40℃放置1个月后该新物质的含量显著升高. |
| 关 键 词： | 鱼腥草 鱼腥草注射液 挥发油 吐温80 核磁共振氢谱 |
| 收稿时间： | 2010/6/17 0:00:00 |
Effect of Tween 80 on Yuxingcao injection and volatile oils from Houttuynia cordata |
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| TAN Zhigao,CHAO Zhimao,SUI Yu,LIU Haiping,WU Xiaoyi,SUN Jian and YAN Han.Effect of Tween 80 on Yuxingcao injection and volatile oils from Houttuynia cordata[J].China Journal of Chinese Materia Medica,2011,36(2):175-179. | |
| Authors: | TAN Zhigao CHAO Zhimao SUI Yu LIU Haiping WU Xiaoyi SUN Jian and YAN Han |
| Institution: | Experimental Research Center, China Academy of Chinese Medical Science, Beijing 100700, China;Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China;Experimental Research Center, China Academy of Chinese Medical Science, Beijing 100700, China;Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China;Experimental Research Center, China Academy of Chinese Medical Science, Beijing 100700, China;Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China;Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China;Experimental Research Center, China Academy of Chinese Medical Science, Beijing 100700, China;Experimental Research Center, China Academy of Chinese Medical Science, Beijing 100700, China |
| Abstract: | Objective: To research the effect of polysorbate 80(Tween 80) on Yuxingcao injection and volatile oils from Houttuynia cordata.Method: 1H-NMR spectra of aldehydic and new matter in Yuxingcao injection,volatile oils of H.cordata,and solutions of Tween 80 and volatile oil of H.cordata are determined and compared from various angles of growing origin,storage temperature,and storage time.Result: Three aldehydic singlets in 1H-NMR spectra of every volatile oil from 4 aerial part of H.cordata were observed.These ... |
| Keywords: | Houttuynia cordata Yuxincao injection volatile oil Tween 80 1H-NMR spectrum |
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