吻合器痔上黏膜环切钉合术加外痔切除术治疗混合痔的疗效分析

目的研究吻合器痔上黏膜环切钉合术（PPH）加外痔切除术治疗Ⅲ、Ⅳ度混合痔的临床疗效。方法将112例混合痔患者随机分成PPH1组34例、PPH2组36例、剥扎组42例，PPH1组采用单纯PPH术，PPH2组采用PPH加外痔切除术，剥扎组采用外剥内扎术治疗。观察和比较3组患者术后24h疼痛程度及术后排便疼痛指数、出血、伤口水肿、尿潴留、肛门坠胀、肛门控便能力、手术时间、住院时间和费用等指标；肛肠测压仪检测手术前后3组患者肛管动力学变化指标；随访0．5。1年并记录痔复发或发生血栓外痔情况。结果PPHl组术后24h疼痛指数低于另外2组（P〈0．05）：3组患者在出血、肛门坠胀、肛门控便能力方面差异无统计学意义（P〉0．05）。在术后排便疼痛、伤口水肿、手术时间、住院时间方面，PPHl组和PPH2组优于剥扎组（P〈0．05）：在术后尿潴留、费用方面剥扎组处于优势（P〈0．05）。手术前后剥扎组肛管静息压变化值小于另外2组（P〈0．05），手术前后3组患者直肠感觉阈和直肠耐受量变化值差异无统计学意义（P〉0．05）。随访半年至1年，PPH1组无复发患者，有3例发生血栓外痔；PPH2组无复发患者；剥扎组复发2例，发生血栓外痔1例。结论PPH加外痔切除术是治疗混合痔的安全有效术式，适合外痔严重的混合痔。

Efficacy of the procedure for prolapse and hemorrhoids combined with external hemorrhoids excision in the treatment of Ⅲ or Ⅳ mixed hemorrhoids

Objective To investigate the efficacy of the procedure for prolapse and hemorrhoids (PPH) combined with external hemorrhoids excision in the treatment of Ⅲ or Ⅳ mixed hemorrhoids. Methods One hundred and twelve patients with Ⅲ or Ⅳ mixed hemorrhoids admitted for surreal treatment were randomly divided into three groups: PPH 1 group (34 cases), PPH2 group (36 cases), and Milligan-Morgun group (42 cases). PPH1 group received the standard PPH operation, PPH2 received PPH and external hemorrhoids excision, and Milligan-Morgan group received Milligan-Morgan hemorrhoidectomy. Postoperative 24 h-pain index, pain index when defecating, bleeding, anal discomfort feeling, wound edema, the ability of controlling feces, operating time, hospitalization time and charges were recorded. The change of anal dynamics was detected by anorectal manometry. All the patients were followed-up for 0.5-1 year. Results There were no significant differences among the three groups in bleeding, anal discomfort feeling, the ability of controlling feces(P>0.05). The postoperative 24 h-pain index of PPH1 group was lower than those of the other two groups (P<0.05). PPH1 group and PPH2 group were better than Milligan-Morgan group in pain index when defecating, wound edema, operating time, and hospitalization time (P<0.05). Milligan-Morgan group was better than the other two groups in postoperative urinary retention and hospital charges(P<0.05). The change of anal duct pressure of Milligan-Morgan group was less than those of the other two groupa(P<0.05). Within 0.5-1.0 year follow-up, 3 patients got thrombosed external hemorrhoid in PPH1 group, 2 patients recurred and 1 patient got thrombosed external hemorrhoid in Milligan-Morgan group, no recurred patients in PPH2 group. Conclusion PPH combined with external hemorrhoid excision is a safe and effective treatment for mixed hemorrhoids, which is suitable for mixed hemorrhoids with severe external hemorrhoids.