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基于微生物-肠-脑轴理论中医调节肠道菌群治疗失眠研究进展
引用本文:黄倩,曾霖,王高祥,李惠林. 基于微生物-肠-脑轴理论中医调节肠道菌群治疗失眠研究进展[J]. 天津中医药, 2022, 39(4): 538-544
作者姓名:黄倩  曾霖  王高祥  李惠林
作者单位:广州中医药大学第四临床医学院, 深圳 518033;南京中医药大学, 南京 210000;广州中医药大学第四临床医学院, 深圳 518033;深圳市中医院内分泌科, 深圳 518033
基金项目:深圳市医疗卫生三名工程项目(SZSM201512043);李惠林广东省名老中医药专家传承工作室建设项目。
摘    要:失眠是临床常见病,难治病.微生物-肠-脑轴已被证实与神经、消化、内分泌、呼吸等多系统疾病相关.近年来,有研究表明,肠道菌群与失眠关系密切,而中药能通过调节肠道菌群失稳改善睡眠.文章从微生物-肠-脑轴理论、相关中医理论基础及基于微生物-肠-脑轴理论对中医调节肠道菌群治疗失眠的研究进展等方面进行论述,以期为中医药治疗失眠的...

关 键 词:微生物-肠-脑轴  肠-脑轴  肠道菌群  失眠  中医
收稿时间:2021-12-18

Research progress in the treaditional Chinese madicine treatment of insomnia by adjusting intestinal flora based on microbiota-gut-brain axis theory
HUANG Qian,ZENG Lin,WANG Gaoxiang,LI Huilin. Research progress in the treaditional Chinese madicine treatment of insomnia by adjusting intestinal flora based on microbiota-gut-brain axis theory[J]. Tianjin Journal of Traditional Chin Medicine, 2022, 39(4): 538-544
Authors:HUANG Qian  ZENG Lin  WANG Gaoxiang  LI Huilin
Affiliation:The Fourth Clinical Medicine College of Guangzhou University of Chinese Medicine, Shenzhen 518033, China;Nanjing University of Chinese Medicine, Nanjing 210000, China; The Fourth Clinical Medicine College of Guangzhou University of Chinese Medicine, Shenzhen 518033, China;Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518033, China
Abstract:Insomnia is a clinical disease which is prevalent but difficult to cure. The microbiota-gut-brain axis has been shown to be associated with many systemic diseases,such as neurological,digestive,endocrine,respiratory diseases. In recent years,some studies have shown that gut microbiota is closely related to insomnia,and continuous clinical and experimental studies have shown that traditional Chinese medicine(TCM) can improve insomnia by regulating intestinal flora instability. This paper discusses the overview of the microbiota-gut-brain axis,the theoretical basis of TCM and the research progress of regulating intestinal flora in TCM based on the theory of microbiota-gut-brain axis and so on,in order to provide new ideas for the treatment of insomnia.
Keywords:microbiota-gut-brain axis  gut-brain axis  gut microbiota  insomnia  traditional Chinese medicine
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