CO2点阵激光与1550nm铒玻璃点阵激光治疗妊娠纹的自身对照研究

目的： 评价CO2点阵激光与1550nm铒玻璃点阵激光治疗妊娠纹的疗效及安全性。方法：收集妊娠纹患者，以前正中线分腹部为左右两侧，左侧妊娠纹采用10600nm CO2点阵激光，右侧妊娠纹采用1550nm铒玻璃点阵激光治疗。每次治疗间隔2个月，治疗3次，末次治疗后随访3个月。结果：剔除2例失访患者，共25例患者完成本研究。84%患者右侧和48%患者左侧的皮损改善51％～75％，差异有统计学意义（P<0.05）。自我满意度评分中80%患者对右侧满意，68%对左侧满意。治疗后20%患者左侧色素沉着，8%患者右侧色素沉着。患者在治疗过程中疼痛评分右侧（5.41±2.13分）高于左侧（4.19±2.12分），两者差异有统计学意义（P<0.001）。两侧均未出现永久性色素改变。结论：1550nm铒玻璃点阵激光较10600 nmCO2点阵激光更能有效治疗妊娠纹。

Therapeutic efficacy for striae distensae with fractional CO2 laser and 1550nm Er glass laser: a comparative study

Objective: To evaluate the efficacy and safety of fractional CO2 laser and 1550nm Er glass laser in the treatment of the patients with striae distensae. Methods: The patients with striae distensae were collected. The striae distensae on the left abdomen was treated with 10600nm CO2 fractional laser and that on the right site was treated with 1550nm Er glass fractional laser, once two months for 3 times. All the patients were followed up for 3 months. Results: A total of 25 patients completed the treatment and two patients were lost for follow-up. The improvement of 51%-71% was achieved on the right abdomen in 84% patients, on the left site in 48% patients, with a significant difference (P<0.05). There was also a difference in self-satisfaction (P<0.05) in favorite of right site (80%?versus 68%，P<0.05). Hyperpigmentation was seen in 20% of the patients assessed on the left abdomen and only in 8% on the right abdomen. During the treatment, average score of the pain on the right abdomen was 5.41±2.13, which was higher than that on the left (4.19±2.12), with a significant difference (P<0.001). No permanent hypopigmentation was found on the both sides. Conclusion: 1550nm Er glass fractional laser is more effective than fractional CO2 laser in the treatment for striae distensae.