长脉宽1064nmNd:YAG激光治疗婴儿血管瘤疗效评价

目的：评价长脉宽1064nmNd:YAG激光治疗婴儿血管瘤的临床疗效及不良反应。方法：回顾性分析61例经长脉宽1064nmNd:YAG激光治疗的婴儿血管瘤，治疗参数：3mm光斑，脉宽30-40ms，能量密度180-220J/cm2，DCD30/20/30ms，间隔时间为4周，治疗次数1-7次不等，所有患儿均为浅表血管瘤的隆起性皮损。 结果：57例患儿皮损改善76%～100%，4例改善51%～75%。不良反应包括： 水疱20例 （32.79%），1天～10天修复；浅表瘢痕9例（14.75%）；色素减退5例（8.20%）；色素沉着4例（6.56%）；毛发稀少或缺失3例（4.92%）。随访3个月时色素改变及瘢痕均有不同程度的改善，但毛发改变无明显改善。结论：长脉宽1064nmNd:YAG激光治疗婴儿血管瘤有效，但不良反应率较高。

Assessment of long pulse width 1064 nm Nd:YAG laser in the treatment of infantile hemangioma

Objective: To assess the clinical efficacy and adverse reaction of long pulse width 1064nmNd:YAG laser in the treatment of infantile hemangioma. Methods: The data of sixty-one cases with infantile hemangioma treated with long pulse width 1064nmNd:YAG laser with 3mm light spot, pulse width 30-40ms, energy density 180-220J/cm2, DCD30/20/30ms, once 4 weeks were analyzed retrospectively. The hemangioma in all patients was protuberant and superficial. Results：The improvement of 76%～100% was seen in 57 cases and of 51%～75% in 4 cases. The adverse reactions included transient blister, which was subsided during one to 10 days in 20 cases (32.79%), superficial scar formation in 9 (14.75%), depigmentation in 5 (8.20%), pigmentation in 4 (6.56%) and sparse hair or absence in 3 (4.92%). After 3 months of follow-up, pigmentation and scar were improved, but the sparse hairs were not significantly improved. Conclusion: Long pulse width 1064nmNd:YAG laser is an effective method in the treatment of infantile hemangioma, but the adverse reactions are more.