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浅层X线放射治疗基底细胞癌和鳞状细胞癌27例疗效分析
引用本文:单晓峰,杨宝琦,田洪青,张福仁.浅层X线放射治疗基底细胞癌和鳞状细胞癌27例疗效分析[J].中国麻风皮肤病杂志,2018,34(10):577.
作者姓名:单晓峰  杨宝琦  田洪青  张福仁
作者单位:山东省皮肤病医院,济南,250022
摘    要:目的:评价浅层X射线治疗皮肤基底细胞癌(BCC)和鳞状细胞癌(SCC)的疗效。方法:回顾分析2014年6月至2017年7月在我院应用浅层X射线治疗的27例原发性BCC(14例)和SCC(13例)患者,所有患者均经过组织病理学确诊,因健康状况、年龄、皮损部位等原因不适用手术而选用浅层X线治疗。结果:27例患者的31处皮损均痊愈,受照总剂量为45.6-53.2 Gy,随访 2年 仅1例患者1处皮损复发。不良反应主要为放射性皮炎及皮损处的溃烂,皮损体积较大者多伴有疼痛,一般1个月内消失。结论:浅层X射线放射治疗SCC和BCC疗效好,复发率低,对因各种原因不适合手术治疗的患者,是较为理想的方法。

关 键 词:浅层X线  基底细胞癌  鳞状细胞癌  

Efficacy of superficial X-ray in the treatment of 27 patients with basal and squamous cell carcinoma
SHAN Xiaofeng,YANG Baoqi,TIAN Hongqing,ZHANG Furen.Efficacy of superficial X-ray in the treatment of 27 patients with basal and squamous cell carcinoma[J].China Journal of Leprosy and Skin Diseases,2018,34(10):577.
Authors:SHAN Xiaofeng  YANG Baoqi  TIAN Hongqing  ZHANG Furen
Institution:Shandong Provincial Hospital for Skin Diseases, Jinan 250022, China
Abstract:Objective: To assess the efficacy of superficial X-ray therapy in the treatment of?basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Methods: The data of 14 patients with BCC and 13 with SCC diagnosed by biopsy and treated with superficial X-ray therapy in our hospital from June 2014 to July 2017 was analyzed retrospectively. Results: Thirty one lesions in 27 patients were disappeared. The total X-ray dose was 45.6-53.2 Gy. There was only one lesion in one SCC patient relapsed after 2 years follow-up. The adverse effects were radiodermatitis and ulceration that usually disappeared in 1 month. Conclusions: Superficial X-ray treatment is effective and has low recurrence in the treatment for BCC and SCC, which is an option for the patient who are not suitable for surgical intervention.
Keywords:superficial X-ray  basal cell carcinoma  squamous cell carcinoma  
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