妊娠合并甲状腺功能减退症或亚临床甲状腺功能减退症77例临床分析 |
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引用本文: | 刘娜,边旭明,高劲松,戚红,龚晓明,刘俊涛,杨剑秋. 妊娠合并甲状腺功能减退症或亚临床甲状腺功能减退症77例临床分析[J]. 中华围产医学杂志, 2005, 12(1): 186-189. DOI: 10.3760/cma.j.issn.1007-9408.2009.03.008 |
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作者姓名: | 刘娜 边旭明 高劲松 戚红 龚晓明 刘俊涛 杨剑秋 |
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作者单位: | 中国医学科学院北京协和医学院北京协和医院妇产科,100730; |
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摘 要: | Objective To investigate the maternal and fetal outcomes of pregnant women with hypothyroidism or subclinical hypothyroidism. Methods From Jan. 2005 to Mar. 2008, clinical records of 77 women with hypothyroidism (n=57) or subclinical hypothyroidism (n = 20) during pregnancy who delivered at Peking Union Medical College Hospital were reviewed. The basic information, maternal complications and neonatal outcomes of the patients were compared with 79 healthy women who delivered during the same period. Results The prevalence of maternal hypothyroidism during the study period was 0.74% ,and that of maternal subclinical hypothyroidism was 0.26%. The mean neonatal birth weight of women with hypothyroidism was lower than that of the control [(3191.8±659.47 g) vs (3301.9±423. 1 g), P<0.05], the incidence of abnormal glucose metabolism was higher (24.6% vs 11.4% ,P<0.05), and small for gestational age infants were more common than in the control group (12. 3% vs 2. 5%, P<0. 05). The maternal and fetal outcomes of women with subclinical hypothyroidism during pregnancy showed no difference compared with the control. Conclusions Early screening for the high risk women and appropriate management are important to improve the neonatal and fetal outcomes of women with hypothyroidism and subclinical hypothyroidism during pregnancy.
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关 键 词: | 妊娠并发症 甲状腺功能减退症 妊娠结局 |
Clinical analysis of hypothyroidism or subclinical hypothyroidism during pregnancy |
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Keywords: | Pregnancy complicationsHypothyroidismPregnancy outcome |
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