ICU鲍曼不动杆菌医院感染的危险因素分析

目的探讨重症监护病房（ICU）鲍曼不动杆菌医院感染的危险因素。方法收集ICU鲍曼不动杆菌医院感染患者405例，选择同期ICU未患鲍曼不动杆菌医院感染患者397例作为对照组。采用病例对照研究发现暴露信息，logistic多元回归分析其潜在危险因素。结果ICU入住时间、使用多种抗生素、机械通气时间、再次插管、胸和腹部引流、多次手术、使用激素、昏迷和开放气道是鲍曼不动杆菌医院感染的危险因素（t分别=5．96、7．39，χ2分别=4．42、6．71、5.32、7．76、9．13、10．83、12．51，P均〈0．05），经多因素Logistic分析后，开放气道、昏迷、使用激素、再次插管、胸和腹部引流、使用多种抗生素、ICU入住时间为主要的危险因素。结论了解危险因素并针对危险因素采取相应措施有助于控制鲍曼不动杆菌引起的医院感染。

Risk factors analysis of nosocomial infection caused by acinetobater baumanii in intensive care unit

Objective To investigate the risk factors of nosocomial infection caused by acinetobater baumanii in inten- sive care unit （ICU）. Methods A total of 405 cases with nosocomial infection caused by acinetobater baumanii were selected and 397 patients did not suffering from infection caused by acinetobater baumanii as controls. Through case-control study to find explosure message and using logistic regression analysis to analyze its latent risk factors. Results Univariate analysis showed that the risk factors of infection caused by acinetobater baumanii were ICU stay time, using a variety of antibiotics, duration of mechanical ventilation, intubation again, thorax/abdomen drainage tube, repeated surgery, use of hormones, unconsciousness and open airway （t=5.96,7.39;χ2=4.42,6.71,5.32,7.76,9.13,10.83,12.51 ,P〈0.05）. Logistic regression analysis showed that the risk factors were open airway, unconsciousness, use of hormones, intubation again, thorax/abdomen drainage tube, using a variety of antibiotics and ICU stay time. Conclusions Investigating risk factors is benefit for preventing nosocomial infection caused by acinetobater baumanii in ICU.