| 346例绝经后乳腺癌的临床特征分析 |
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| 引用本文： | 王晓霞,林玉梅,程广杰. 346例绝经后乳腺癌的临床特征分析[J]. 国外医学:老年医学分册, 2010, 31(1): 1-4 |
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| 作者姓名： | 王晓霞 林玉梅 程广杰 |
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| 作者单位： | 王晓霞,林玉梅(吉林大学中日联谊医院肿瘤血液科,长春,130031,中国);程广杰(长春市妇产医院,长春,130042,中国) |
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| 摘 要： | 目的：明确绝经后乳腺癌的临床特征及与绝经前乳腺癌的异同性。方法：对绝经前、后乳腺癌患者的首发症状、病程、临床分期及受体状态等指标进行回顾性对照分析。组间比较采用X^2检验，P〈0．05认为差异有统计学意义。结果：浸润性导管癌是绝经前后两组患苦的主要病理类型，T4和N0患者在绝经后组较绝经前组明显增高（x^2=10．62，P〈0．01；x^2=5．72，P〈0．05），N1患者则明显低于绝经前组（x^2=6．09，P〈0．05）；在相同肿瘤大小情况下，绝经后组的转移率均低于绝经前组；绝经后组PR阳性者较绝经前组明显减少（x^2=13．9，P〈0．01），ER和HER-2表达则无差异；绝经前、后两组分子亚型与腋窝淋巴结转移无关。结论本研究结果初步显示绝经后乳腺癌的临床特征与绝经前患者总体上存在相似性，但又具有其独特性，对绝经后乳腺痛的生物学特性及其对疗效和预后的影响需进一步探讨。
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| 关 键 词： | 乳腺癌 绝经后 临床特征 |
Clinical Features of Three Hundred and Forty-six Postmenopausal Patients with Breast Cancer |
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| Wang Xiaoxia Lin Yumei Cheng Guangjie. Clinical Features of Three Hundred and Forty-six Postmenopausal Patients with Breast Cancer[J]. Foreign Medical Sciences(Geriatrics), 2010, 31(1): 1-4 |
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| Authors: | Wang Xiaoxia Lin Yumei Cheng Guangjie |
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| Affiliation: | Wang Xiaoxia~1 Lin Yumei~1 Cheng Guangjie~2 1 Department of Oncology and Hematology,China-Japan Union Hospital Affiliated to Jilin University,Changchun 130031,China 2 Changchun Obstetrical and Gynecological Hospital,Changchun 130042,China |
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| Abstract: | OBJECTIVE:To identify the similarities and differences of clinical features between post - menopause and pro - menopause breast cancer.METHODS:The clinical indexes including first symptom,course of disease,clinical stage and receptor expression of the patients with post - menopause and pro - menopause breast cancer were analysed retrospectively.These indexes were compared between the pro - menopause group and post - menopause group by the x~2 test,and the differences of them were statistically significant (... |
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| Keywords: | Breast neoplasms Menopause Clinical features |
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