肝素结合蛋白及血清淀粉样蛋白A在AECOPD合并肺部感染中的研究进展 |
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引用本文: | 马葳,李梅华,蒋菁,刘兴许,杨丽芬,李丽. 肝素结合蛋白及血清淀粉样蛋白A在AECOPD合并肺部感染中的研究进展[J]. 昆明医科大学学报, 2023, 44(2): 172-176. DOI: 10.12259/j.issn.2095-610X.S20230228 |
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作者姓名: | 马葳 李梅华 蒋菁 刘兴许 杨丽芬 李丽 |
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作者单位: | 昆明市第一人民医院呼吸与危重症医学科,云南 昆明 650011 |
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基金项目: | 国家自然科学基金资助项目(82060127) |
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摘 要: | 慢性阻塞性肺疾病是一种常见、多发、死亡率较高的呼吸系统慢性疾病,感染是造成慢阻肺急性加重最主要的诱因;近年来,血清淀粉样蛋白A及肝素结合蛋白作为较新的感染指标,因其反应迅速,检验灵敏度、特异度较高等优势,在呼吸系统疾病领域越来越受到关注。将对HBP、SAA在慢阻肺急性加重合并肺部感染方面的研究进展进行概括归纳,为临床诊断和评估预后提供参考。
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关 键 词: | 慢性阻塞性肺疾病 慢性阻塞性肺疾病急性加重 肝素结合蛋白 血清淀粉样蛋白A |
收稿时间: | 2022-12-09 |
Advances in the study of heparin-binding protein and serum amyloid A in AECOPD co-infection of the lung |
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Affiliation: | Deft. of Respiratory and Critical Care Medicine ,The First People’s Hospital of Kunming,Kunming Yunnan 650011,China |
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Abstract: | Chronic obstructive pulmonary disease is a common, frequent and high mortality chronic disease of the respiratory system, while infection is the main cause of acute exacerbation of COPD; In recent years, serum amyloid A and heparin-binding protein have received increasing attention in the field of respiratory diseases as newer indicators of infection because of their rapid response, sensitivity and specificity; This article will summarize the research progress of HBP and SAA in acute exacerbation of chronic obstructive pulmonary disease combined with pulmonary infections, and provide a reference for clinical diagnosis and assessment of prognosis. |
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