2014-2019年武汉市居民宫颈癌死亡特征及潜在减寿年数

目的  了解2014-2019年武汉市居民宫颈癌死亡流行特征及潜在减寿年数(potential years of life lost, PYLL)，为宫颈癌防制提供数据支持。方法  利用武汉市死因监测系统收集2014-2019年武汉市居民宫颈癌死亡情况，计算武汉市居民不同年龄、地区之间宫颈癌粗死亡率及标化死亡率的变化趋势，并测算由宫颈癌导致的潜在减寿年数并分析宫颈癌流行病学特征。结果  武汉市宫颈癌粗死亡率由2014年的0.60/10万上升至2019年的2.13/10万，年度变化百分比(annual percentage change, APC)为32.63%，变化趋势差异有统计学意义(t=-3.05, P=0.038)。随着年龄增长，武汉市宫颈癌死亡率呈现波动上升趋势。由宫颈癌导致的潜在减寿年数由2014年的640.00人年升高至2019年的2 660.00人年。2014-2019年的PYLL为15.26年，标化潜在减寿率为0.23‰。结论  2014-2019年武汉市居民宫颈癌死亡率呈上升趋势，应积极针对中低年龄段已婚女性开展宫颈癌筛查，加强宫颈癌防制措施，降低宫颈癌导致的疾病负担。

Analysis of death characteristics and potential years of life lost of cervical cancer in Wuhan residents from 2014 to 2019

  Objective  To investigate the prevalence characteristics and the potential years of life lost (PYLL) of cervical cancer in Wuhan from 2014 to 2019, and to provide a scientific basis for prevention and control.  Methods  The Cervical cancer deaths among Wuhan residents during 2014-2019 were collected from the population-based Mortality Surveillance System. We analyzed the change tendency of crude and standardized mortality rate of cervical cancer in different area and age groups. And PYLL was also calculated to describe the epidemiological characteristics of cervical cancer.  Results  The crude mortalities of cervical cancer was increased from 0.60/105 in 2014 to 2.13/105 in 2019, with APC equal to 32.63% (t=-3.05, P=0.038). The mortality rate of cervical cancer showed an upward trend with the increaseing age groups. The PYLL of cervical cancer increased from 640.00 person-years in 2014 to 2 660.00 person-years in 2019. The average PYLL caused by cervical cancer was 15.26 years, and the standardized PYLL rate was 0.23‰.  Conclusions  The mortality rate of cervical cancer presented an upward trend with the increasing age. Cervical cancer screening should be promoted in younger women. It is necessary to take the corresponding preventive and control measures for reducing the burden of disease.