改良泪囊鼻腔吻合术联合丝裂霉素C治疗慢性泪囊炎56例

目的:总结和分析改良泪囊鼻腔吻合术联合术中应用丝裂霉素C治疗慢性泪囊炎的效果。方法:随机选择56例(56眼)慢性泪囊炎患者施行改良泪囊鼻腔吻合术联合术中应用丝裂霉素C(观察组),随机对照组53例(53眼)行传统泪囊鼻腔吻合术,术后随访12mo,观察患者术后泪道通畅情况,鼻内窥镜下测量骨孔面积、观察骨孔内肉芽增生情况。结果:随访12mo,观察组手术成功率为100%,对照组手术成功率为79.2%,观察组和对照组手术成功率比较其差异有显著性意义(P<0.05)。结论:改良泪囊鼻腔吻合术联合术中应用丝裂霉素C能提高慢性泪囊炎的手术成功率,保持吻合口通畅,是值得推荐的一种手术方法。

Clinical effects of improved dacryocystorhinostomy with mitomycin C for chronic dacryocystitis

AIM:To observe the therapeutic effect of improved dacryocystorhinostomy with mitomycin C(MMC) for chronic dacryocystitis.METHODS:A total of 56 cases(56 eyes) with chronic dacryocystitis underwent improved dacryocystorhinostomy with MMC as observation group and 53 cases(53 eyes) underwent traditional dacryocystorhinostomy as control group.The condition of lacrimal passage and proliferation of granulation in bone holes were observed.The areas of bone holes were measured under the rhinoscope.The therapeutic effects of two kinds of operation methods were compared.RESULTS:After the follow-up of one year,the rate of surgical success was 100% in the observation group and 79.2% in the control group.There was statistical difference of success rate between two groups.CONCLUSION:The improved dacryocystorhinostomy with mitomycin C(MMC) can increase the surgical success rate for chronic dacryocystitis.It is an important improvement of operation procedure.