| 细胞周期素D1在口腔鳞状细胞癌组织中的表达及意义 |
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| 作者姓名： | Xing JS Shi PR Chen XJ He DN Li LH Nan XR |
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| 作者单位： | 1.山西医科大学第二医院口腔科; 2.山西医科大学口腔医学系口腔颌面外科教研室, 太原030001 |
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| 基金项目： | 山西省科技工业攻关基金资助项目 |
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| 摘 要： | 目的 研究口腔鳞状细胞癌(OSCC)组织中细胞周期素D1(Cyclin D1)的表达及意义.方法 应用免疫组织化学Envosion法检测50例OSCC患者与10例正常黏膜组织中Cyelin D1蛋白在病理组织切片中的表达水平,并进行统计学分析.结果 在50例OSCC标本中Cyclin D1主要表达在细胞核,也有少量表达...
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| 关 键 词： | 口腔鳞状细胞癌 细胞周期素D1 免疫组织化学 |
| 收稿时间： | 2011-06-25 |
| 修稿时间： | 2011-06-25 |
Expression and its significance of Cyclin D1 in oral squamous cell carcinoma |
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| Xing JS,Shi PR,Chen XJ,He DN,Li LH,Nan XR.Expression and its significance of Cyclin D1 in oral squamous cell carcinoma[J].West China Journal of Stomatology,2011,29(3):299-301. |
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| Authors: | Xing Jin-Song Shi Pei-Rong Chen Xian-Jiu He Dong-Ning Li Li-Hua Nan Xin-Rong |
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| Affiliation: | 1. Dept. of Stomatology, The Second Hospital of Shanxi Medical University, Taiyuan 030001, China; 2. Dept. of Oral and Maxillofacial Surgery, Dental Medical Department of Shanxi Medical University, Taiyuan 030001, China |
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| Abstract: | Objective To investigate the expression and significance of Cyclin D1 in oral squamous cell carcinoma(OSCC).Methods A immunohistochemistry method,Envosion,was employed to test the manifesting levels of Cyclin D1 in pathological slices of 50 OSCC cases and 10 normal cases,and the results was treated with statistical ana-lysis.Results In 50 OSCC cases,Cyclin D1 mainly manifested in karyon,and a little in cytoplasm.The positive manifesting rates of Cyclin D1 in the samples was 80.0%,which was significantly hig... |
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| Keywords: | oral squamous cell carcinoma Cyclin D1 immunohistochemistry |
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