| 儿童肾病合并肺孢子菌肺炎3例临床分析 |
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| 引用本文： | 周楠,孟繁英,沈颖,陈植,袁林.儿童肾病合并肺孢子菌肺炎3例临床分析[J].临床儿科杂志,2011,29(8). |
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| 作者姓名： | 周楠 孟繁英 沈颖 陈植 袁林 |
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| 作者单位： | 首都医科大学附属北京儿童医院肾脏内科,北京,100045 |
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| 摘 要： | 目的 提高对肺孢子菌肺炎(PCP)的认识.方法 回顾分析3 例肾病并发PCP患儿的临床资料.结果 3例患儿的共同特点是,PCP起病急,临床以发热、咳嗽起病,伴有低氧血症,症状与体征不平行;早期临床表现无特异性,易漏诊,并发PCP前患儿均长期或大量应用免疫抑制剂、足量泼尼松口服疗程达8周及以上;免疫功能检查均有不同程度的CD4细胞比例下降.结论 提高对PCP的认识,做到早期诊断;适当控制免疫抑制剂应用、改善患儿生活环境、针对高危人群定期检测CD4细胞水平以及酌情应用复方磺胺甲基异噁唑预防均有利于降低肺孢子菌肺炎的发病率.
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| 关 键 词： | 肺孢子菌肺炎 肾病 儿童 |
Clinical analysis of Pneumocystis pneumonia in 3 children with nephropathy |
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| ZHOU Nan,MENG Fan-ying,SHEN Ying,CHEN Zhi,YUAN Lin.Clinical analysis of Pneumocystis pneumonia in 3 children with nephropathy[J].The Journal of Clinical Pediatrics,2011,29(8). |
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| Authors: | ZHOU Nan MENG Fan-ying SHEN Ying CHEN Zhi YUAN Lin |
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| Institution: | ZHOU Nan,MENG Fan-ying,SHEN Ying,CHEN Zhi,YUAN Lin(Beijing Children's Hospital Affiliated to Capital University of Medical Science,Beijing 100045,China) |
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| Abstract: | Objective To further understand Pneumocystis pneumonia(PCP).Methods Clinical symptoms and laboratory data of 3 pediatric primary or secondary nephropathy cases with PCP were retrospectively analyzed.Results When infected with PCP,the three patients had the common characters of fever and cough at beginning with progressive hypoxia.Clinical presentations in the early stage were not special and may lead to misdiagnosis.Before PCP developed,the three patients had received immunosuppressant and high dose of oral... |
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| Keywords: | Pneumocystis pneumonia nephropathy children |
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