Potential activity of Ca2+/Mg2+-dependent endonuclease in endometrial hyperplasia and cancer |
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| Authors: | E. A. Kolobova A. V. Zhdanov D. A. Varlamov M. M. Dement'eva G. E. Chernukha L. Z. Faizullin Yu. Yu. Tabakman A. E. Ivanova G. T. Sukhikh |
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| Affiliation: | (1) Research Center of Obstetrics, Gynecology, Russian Academy of Medical Sciences, USSR;(2) Research Center of Perinatology, Russian Academy of Medical Sciences, USSR;(3) Institute of Biological Medicine, Moscow, USSR;(4) Moscow Municipal Oncology Dispensary, Moscow, USSR |
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| Abstract: | Potential activity of Ca2+/Mg2+-dependent endonuclease in hyperplastic endometrial tissues is lower than in normal endometrium and practically absent in endometrial cancer tissue. Thus, molecular mechanisms of apoptosis regulation are disturbed even at the stage of hyperplasia. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 127, No. 6, pp. 683–687, June, 1999 |
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| Keywords: | apoptosis Ca2+/Mg2+-dependent endonuclease endometrial hyperplasia endometrial cancer |
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