音叉、尼龙丝、痛觉、踝反射筛查糖尿病周围神经病变的应用

目的 探讨音叉、尼龙丝、痛觉、踝反射在筛查糖尿病周围神经病变（diabetic peripheral neuropathy,DPN）中的应用.方法 选取2013年2月至10月在我院住院治疗的200例2型糖尿病患者,对其同时进行音叉、尼龙丝、痛觉、踝反射检查,以筛查糖尿病周围神经病变,以MNSI临床评分方法为标准,比较4种方法的灵敏度、特异性、阳性预测值、阴性预测值、约登指数及Kappa值.结果 音叉、尼龙丝、痛觉、踝反射4种检查中联合两项以上筛查DPN一致性及真实性均较好.结论 四种筛查糖尿病周围神经病变的检查,操作简便、经济快捷;联合两项以上检查可明显提高DPN筛查的敏感性及准确性.

Application of tuning fork,nylon yarn,pain and ankle reflex in screening of diabetic peripheral neuropathy

Objective To explore the value of tuning fork,nylon yarn,pain and ankle reflex in screening of diabetic peripheral neuropathy （DPN）.Methods To collect 200 cases of type 2 diabetes in the clinics of our hospital from Februarv 2013 to October 2013.Every patient was examined with tuning fork,nylon yarn,pain and ankle reflex.Then we compared the four kinds of screening with the sensitivity,specificity,positive predictive value,negative predictive value,Youden index and Kappa values by taking MNSI as standard.Result The consistency and authenticity of two or more combined above screening examinations for DPN were good.Conclusion Four kinds of screening methods for DPN are simple,economical and efficient.Combination with two or more tests can significantly improve the sensitivity and accuracy in clinical screening for DNP.