暖贴加热法在溶解甘露醇结晶中的应用观察

目的 探讨暖贴加热法溶解甘露醇结晶在临床应用中的可行性.方法 选择2012年10月至2013年4月期间结晶的甘露醇400袋,按单双号随机分成对照组和试验组,各200袋.对照组采用温水浸泡溶解的方法,试验组采用贴暖贴加热溶解的方法,观察比较两种不同方法甘露醇结晶的溶解时间、输注过程中再次析出结晶的例数及出现局部疼痛或静脉炎等情况.结果 与对照组比较,试验组溶解甘露醇结晶时间均明显缩短、温度保持时间延长、输注过程再次析出结晶的例数减少、局部刺激疼痛和静脉炎发生率明显降低,差异有统计学意义（P＜0.05）.结论 暖贴加热法溶解甘露醇结晶操作简单、方便快捷、安全可行、并发症少、应用效果显著,值得在临床推广应用.

Warm paste heating method for dissolving mannitol crystallization

Objective To investigate the feasibility of warm paste heating method in the dissolution of mannitol crystallization. Methods 400 bags of mannitol which crystallized during October 2012 to Apirl 2013 were selected and then were randomly divided into a control group and an experimental group according to the even and odd numbers, 200 for each group. The control group used warm-water soak to dissolve mannitol crystallization, while the experimental group used warm paste heating method. The dissolution time of mannitol crystallization, the number of recrystallization during infusion process, and the situation of local pain or phlebitis were observed and compared between the two groups. Results The dissolution time of mannitol crystallization was shorter, the temperature holding time was longer, fewer bags recrystallized during the irffusion process, and the incidence of local irritation pain or phlebitis was lower in the experimental group than in the control group, with statistical differences （P 〈 0.05）. Conclusions Warm paste beating method for dissolving mannitol crystallization is simple to operate, convenient, fast, safe, feasible, and effective and has fewer complications. It is worth being clinically generalized.