| 24例晚期卵巢癌腹腔注射顺铂的疗效分析 |
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| 引用本文： | 沙玉成. 24例晚期卵巢癌腹腔注射顺铂的疗效分析[J]. 中国药理学通报, 1987, 0(6) |
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| 作者姓名： | 沙玉成 |
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| 作者单位： | 安徽医科大学附属一院妇产科 合肥 |
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| 摘 要： | 阐述顺铂腹腔注射的临床药理学基础,说明顺铂腹腔注射后可以提高腹腔内药物的浓度,有利于癌性腹水和残留癌灶的消失。并报道了我科自1984年5月～1986年12月收治的24例(Ⅲ期18例、Ⅳ期6例)晚期卵巢癌病人的治疗情况。全部病例均经手术和病理证实,都进行了腹腔内注射顺铂和肿瘤细胞减灭术,部分病人还作了其他化疗。经随访观察,完全有效率为58.33％,部分有效率为25％,总有效率为83.33％。
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| 关 键 词： | 腹腔内注射 顺铂 卵巢癌 |
AN ANALYSIS OF 24 CASES OF ADVANCED OVARIAN CANCER TREATED WITH INTRAPERITONEAL INJECTION OF CISPLATIN |
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| Sha Yucheng. AN ANALYSIS OF 24 CASES OF ADVANCED OVARIAN CANCER TREATED WITH INTRAPERITONEAL INJECTION OF CISPLATIN[J]. Chinese Pharmacological Bulletin, 1987, 0(6) |
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| Authors: | Sha Yucheng |
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| Abstract: | The paper first made a review of the literature on the pharmacology and clinical use of cisplatin. An analysis was then made of 24 cases (18 cases of stage I and 6 cases of stage IV)of advanced ovarian cancer treated with intraperitoneal injection of cisplatin in combination with cytoreductive operation and other chemotherapy. The follow-up observation indicates that the complete response rate and partial response rate is 58% and 25% respectively,making up a total effective rate of 83%. |
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| Keywords: | pharmacology Intraperitoneal cisplatin ovarian cancer |
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