| 促肝细胞生长素注射液细菌内毒素检查可行性研究 |
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| 引用本文： | 孙佩芳,李连新,张卫东,王建民.促肝细胞生长素注射液细菌内毒素检查可行性研究[J].中国药房,2002,13(12):747-748. |
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| 作者姓名： | 孙佩芳 李连新 张卫东 王建民 |
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| 作者单位： | 北京军区北京总医院,北京市,100700 |
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| 摘 要： | 目的 :研究促肝细胞生长素注射液细菌内毒素检查法的可行性 ,以替代热原检查法。方法 :按《中国药典》(二部 )2000年版规定 ,用2个厂家生产的鲎试剂 (TAL)对促肝细胞生长素注射液进行细菌内毒素检查法干扰试验。结果 :促肝细胞生长素注射液经10倍稀释后对细菌内毒素与鲎试剂的反应无干扰作用。结论 :用凝胶法进行细菌内毒素检查是可行的。
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| 关 键 词： | 促肝细胞生长素注射液 细菌内毒素 干扰试验 |
| 文章编号： | 1001-0408(2002)12-0747-02 |
| 修稿时间： | 2001年10月16 |
Study on the Feasibility of Bacterial Endotoxin Test for Hepatocyte Growth- promoting Factors Injection |
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| SUN Peifang,LI Lianxin,ZHANG Weidong,WANG Jianmin.Study on the Feasibility of Bacterial Endotoxin Test for Hepatocyte Growth- promoting Factors Injection[J].China Pharmacy,2002,13(12):747-748. |
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| Authors: | SUN Peifang LI Lianxin ZHANG Weidong WANG Jianmin |
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| Abstract: | OBJECTIVE:To study the feasibility of bacterial endotoxin test for hepatocyte growth-promoting factors injection as a substitution for pyrogen test METHODS:According to China Pharmacopoeia(second part,2000),interference test was carried on endotoxin detection of hepatocyte growth-promoting factors injection with limulus lysate test agents produced by two different factories RESULTS:There was no interference with the reaction between bacterial endotoxin and limulus lysate test agent in hepatocyte growth-promoting factors injection in 10-fold dilution CONCLUSION:It is feasible to use the gelatine method in bacterial endotoxin test |
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| Keywords: | hepatocyte growth-promoting factors injection bacterial endotoxin interference test |
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