不同穴位组合对脑梗死患者脑葡萄糖代谢的影响——PET研究

目的:观察不同穴位组合对脑梗死恢复期患者脑葡萄糖代谢的影响。方法:脑梗死患者12例,随机分为2组,醒脑开窍组(7例)选取内关、水沟、风池、三阴交、阴陵泉、太冲;常规针刺组(5例)选取合谷、曲池、足三里、阳陵泉和悬钟。针刺前后应用正电子发射型计算机断层显像(PET)技术观察脑局部葡萄糖代谢。结果:醒脑开窍组激活的脑区有梗死中心区、颞上回、丘脑、颞下回、直回、岛叶、枕外侧、顶叶、小脑;常规针刺组激活海马、额下回、尾状核、扣带回、楔前叶、顶叶。结论:不同穴位组合激活不同的脑区,说明了穴位与脑功能区存在特异联系。

PET study of effects of combination of different points on glucose metabolism in the patient of cerebral infarction

Objective To observe effects of combination of different points on glucose metabolism in the patient of cerebral infarction. Methods Neiguan (PC 6), Shuigou (GV 26), Fengchi (GB 20), Sanyinjiao (SP 6), Yinlingquan (SP 9), Taichong (LR 3) were selected for the Xingnao Kaiqiao group (n=7), and Hegu (LI 4), Quchi (LI 11), Zusanli (ST 36), Yanglingquan (GB 34) and Xuanzhong (GB 39) for the routine acupuncture group (n=5). PET-CT was used to observe the local cerebral glucose metabolism. Results The cerebral regions activated in the the Xingnao Kaiqiao group included infarction center, gyrus temporalis superior, thalamus, gyrus temporalis inferior, gyrus rectus, insula, lateral occipital lobe, parietal lobe and cerebellum, and in the routine acupuncture group included gyrus frontalis inferior, caudate nucleus, cingulated gyrus, hippocampus, precuneus and parietal lobe. Conclusion PET is very suitable for exploring acupuncture mechanisms in treatment of cerebral infarction, and further shows the specificity of acupoints-brain functional region.