Corticosteroid treatment in patients with Sydenham's chorea |
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Authors: | Barash Judith Margalith Dov Matitiau Abraham |
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Institution: | Pediatric Rheumatology, Kaplan Medical Center, Rehovot 76100, Israel. |
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Abstract: | Sydenham's chorea occurs in approximately 10% of acute rheumatic fever and is one of its major manifestations. The disease may last for weeks or months, with a high risk of recurrence; usually only supportive treatment is recommended. This report describes five children diagnosed with Sydenham's chorea and treated with a short course of corticosteroids. Marked improvement of the involuntary movements was observed within 24-48 hours, with complete resolution within 7-12 days after commencement of treatment; there were no relapses. Larger, possibly comparative studies are necessary, but in the meantime treatment with corticosteroids in patients with Sydenham's chorea should be considered. |
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