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肝硬化基础上原发性肝癌的时间密度曲线研究
引用本文:方心华,钟群,赵春雷,钱根年,陈自谦,张雪林. 肝硬化基础上原发性肝癌的时间密度曲线研究[J]. 医学影像学杂志, 2011, 21(2): 221-224
作者姓名:方心华  钟群  赵春雷  钱根年  陈自谦  张雪林
作者单位:1. 解放军184医院放射科,江西,鹰潭,335400
2. 厦门大学附属东方医院南京军区福州总医院医学影像中心,福建,福州,350025
3. 南方医科大学附属第一医院,广东,广州,510515
基金项目:福建省青年人才创新项目(2006F3105)
摘    要:目的:应用MSCT的时间密度曲线(TDC)研究发生于肝硬化基础的肝癌的达峰时间(TTP)及峰值高度(PV)的变化,揭示癌变的血流动力学改变。方法:肝炎后肝硬化合并原发性肝癌病例32例,行MSCT动态增强扫描,观察时间密度曲线及分别得到TTP及PV,应用配对t检验进行统计学分析。结果:肝硬化实质与肝癌的TDC形态不同,两者之间TTP及PV均P<0.05,有统计学意义,即肝癌强化早而强化程度低于肝脏实质。结论:通过肝硬化及肝癌TDC形态学及其指标TTP与PV明确提示它们不同的血流动力学变化。

关 键 词:体层摄影术,X线计算机  肝硬化  原发性肝癌  时间密度曲线

The time-density curve study of primary hepatocellular carcinoma based on cirrhosis with MSCT
FANG Xin-hua,ZHONG Qun,ZHAO chun-lei,QIAN Gen-nian,CHEN Zi-qian,ZHANG Xue-lin. The time-density curve study of primary hepatocellular carcinoma based on cirrhosis with MSCT[J]. Journal of Medical Imaging, 2011, 21(2): 221-224
Authors:FANG Xin-hua  ZHONG Qun  ZHAO chun-lei  QIAN Gen-nian  CHEN Zi-qian  ZHANG Xue-lin
Affiliation:FANG Xin-hua1,ZHONG Qun2,ZHAO Chun-lei2,QIAN Gen-nian2,CHEN Zi-qian2,ZHANG Xue-lin3 1.Department of Radiology,No 184th Hospital of Nanjing Military District,Yingtan 335400,P.R.China 2.Medical Imaging Center,Affiliated Dongfangl Hospital,Xiamen University,Fuzhou General Hospital of Nanjing Military District,Fuzhou 350025,P.R.China 3.Medical Imaging Center,Nanfang Hospital,Southern Medical University,Guangzhou 510515,P.R.China
Abstract:Objective:To explore the time-density curve(TDC) changes of primary hepatocellular carcinoma based on hepatic cirrhosis with MSCT and to study the differences of TTP and PV between HCC and hepatic parenchyma so that to reveal the hemodynamic change betreen them.Methods:Thirty-two cases were primary hepatocellular carcinoma based on cirrhosis.The target scans of each case were performed dynamic scanning within total 30 times.And the TDCs were got and all cases' time to peak(TTP) and peak value(PV) of hepatic...
Keywords:Tomography  X-ray computed  Hepatic cirrhosis  Hepatocellular carcinoma  Time-density curve  
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