| ABC免疫光镜及免疫电镜证实硬红斑皮损炎症区郎格罕细胞 |
| |
| 引用本文： | 米庆胜 陈明. ABC免疫光镜及免疫电镜证实硬红斑皮损炎症区郎格罕细胞[J]. 中国皮肤性病学杂志, 1995, 9(3): 130-131 |
| |
| 作者姓名： | 米庆胜 陈明 |
| |
| 作者单位： | 泰山医学院附属医院皮肤科，第二军医大学一院皮肤科，中国医科大学一院皮肤科 |
| |
| 摘 要： | 应用Ｌｅｕ６、ＨＬＡ－ＤＲ、Ｓ１００抗体ＡＢＣ免疫光镜及免疫电镜方法对ＥＩ皮损内Ｓ１００蛋白阳性组织细胞性质进行了研究。８例ＥＩ免疫光镜观察显示ＥＩ真皮深部及皮下炎症区Ｓ１００蛋白阳性组织细胞其Ｌｅｕ６及ＨＬＡ－ＤＲ染色亦阳性，且多呈树枝状或椭圆形。３例ＥＩ免疫电镜观察显示Ｌｅｕ６十细胞其细胞核是卷曲的脑回状，胞浆内可见不典型的棒状样的郎格罕颗粒，部分阳性细胞超微结构有受损伤的表现。上述结果表明，ＥＩ皮损内所谓的Ｓ１００蛋白阳性组织细胞为ＬＣ，ＬＣ不仅存在于表皮及真皮，亦存在于皮下组织中，且可能介导了ＥＩ细胞免疫的发生。
|
| 关 键 词： | 硬红斑，S100蛋白阳性组织细胞，郎格罕细胞（LC），免疫组织化学 |
ABC Immunolight and Immunoelectron Microscopic Identification of Langerhans Cells in the Inflammatory Area of Erythema Induratum |
| |
| Mi Qingsheng, Chen Ming, Chen Hongduo. ABC Immunolight and Immunoelectron Microscopic Identification of Langerhans Cells in the Inflammatory Area of Erythema Induratum[J]. The Chinese Journal of Dermatovenereology, 1995, 9(3): 130-131 |
| |
| Authors: | Mi Qingsheng Chen Ming Chen Hongduo |
| |
| Abstract: | The histiocytes with S100 protein in the skin lesions of 8 patiens with erythema induratum(EI) were observed using ABC immunohistiochemistry technique with S100, Leu6, HLA-DR antibodies. The results showed that Leu6 and HLA-DR antigens were in the surface of the histiocytes with S100,the ultrastructure of which was same as that of Langerhans cells(LC).It suggested that the so-called histiocytes in the subcutis and might play an important role in the pathogenesis of EI. |
| |
| Keywords: | Erythema induratum Langerhans cells Histiocytes with S100 Protein Immunohis to chemistry |
| 本文献已被 CNKI 维普 等数据库收录！ |
