The role of hepatic lectins and the activity of the mononuclear phagocyte system in systemic Listeria monocytogenes infection in Balb/c mice |
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Authors: | J Beuth H L Ko G Pulverer |
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Institution: | (1) Hygiene-Institut der Universität, Goldenfelsstrasse 19-21, 41 Köln, Federal Republic of Germany |
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Abstract: | Hepatic lectin blocking experiments with D-galactose in Balb/c mice showed that parenchymal liver cells are obviously not involved in Listeria monocytogenes infection (strain SLCC 4013, 5 × 106 cells i.v.). Using the bacterial immunomodifier Propionibacterium avidum KP-40 the importance of an activated mononuclear phagocyte system in the early stage of Listeria infection could be demonstrated.This study was supported by the Deutsche Forschungsgemeinschaft |
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