肝硬化腹水患者血浆一氧化氮的水平及门脉高压血流动力学的研究

【目的】研究伴和不伴腹水的肝硬化患者血浆NO水平以及门脉血流动力学的变化，探讨血浆NO的水平以及门脉血流动力学的变化对于腹水的影响。【方法】分别检测正常人及肝硬化患者的血浆NO浓度，用彩色多普勒检测各组门静脉内径及血流速度。【结果】伴有腹水的肝硬化患者的血浆NO浓度高于不伴腹水组，且门静脉内径增宽血流速度减慢，两组结果比较有显著差异（P〈0．05）。【结论】血清NO增高以及门静脉血流动力学异常在腹水的发生中起一定的作用。

The study of the level of plasma NO and the portal vein hemodynamic condition in cirrhotic patients with ascites

Objective] To study the level of plasma NO and the change of portal vein hemodynamic condition in cirrhotic patients with or without ascites and to explore the effect on ascites of the level of plasma NO and the change of hemody-namy. Methods] Measure the level of plasma NO of normal and cirrhotic patients respectively, and determine the intrinsic diameter and velocity-portal vein by using color dopier. Results] The plasma NO of cirrhotic patients with ascites higher than that without ascites, widened portal vein intrinsic diameter and reduced velocity as well, there are significant differences between the two group (P < 0.05). Conclusion] The heightened plasma NO and abnormal hemodynamy play a certain role in the occurrence of ascites.