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Clinical impact of different detection methods for disseminated tumor cells in bone marrow of patients undergoing surgical resection of colorectal liver metastases: a prospective follow-up study |
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| Authors: | F Jeroen Vogelaar Wilma E Mesker Arjen M Rijken Gaby W van Pelt Antonia M van Leeuwen Hans J Tanke Rob A Tollenaar Gerrit J Liefers |
| Institution: | (1) Department of Surgery, Leiden University Medical Center, Leiden, the Netherlands;(2) Department of Surgery, Amphia Hospital, Breda, the Netherlands;(3) Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands;(4) Department of Pathology, Rijnland Hospital, Leiderdorp, the Netherlands |
| Abstract: | BackgroundLarge number of patients with colorectal liver metastasis show recurrent disease after curative surgical resection. Identification of these high-risk patients may guide therapeutic strategies. The aim of this study was to evaluate whether the presence of disseminated tumor cells in bone marrow from patients undergoing surgical resection of colorectal liver metastases can predict clinical outcome. |
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