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A single dose of zoledronic acid reverses the deleterious effects of glucocorticoids on titanium implant osseointegration |
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| Authors: | J. S. B. Carvas R. M. R. Pereira V. F. Caparbo P. Fuller C. A. Silveira L. A. P. Lima E. Bonfa S. B. V. Mello |
| Affiliation: | 1. Rheumatology Division, Faculdade de Medicina da Universidade de S?o Paulo, Av. Dr. Arnaldo, 455, 3o andar, Reumatologia, S?o Paulo, SP, 0124-6903, Brazil 2. Periodontics, Dental Branch, Faculdade de Odontologia da Universidade de S?o Paulo, S?o Paulo, Brazil |
| Abstract: | SummaryThis study evaluates the effect of zoledronic acid (ZOL) on the osseointegration of titanium implants in rabbits with glucocorticoid (GC)-induced bone loss, and our findings demonstrated that a single dose of ZOL is able to reverse the detrimental effects of GCs on the osseointegration of titanium implants. |
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