| HPLC法测定乳酸依沙吖啶注射液的含量 |
| |
| 引用本文： | 刘玉春,李艳娜. HPLC法测定乳酸依沙吖啶注射液的含量[J]. 安徽医药, 2008, 12(3): 225-226 |
| |
| 作者姓名： | 刘玉春 李艳娜 |
| |
| 作者单位： | 安徽省阜阳市药品检验所,安徽,阜阳,236015;安徽省阜阳市药品检验所,安徽,阜阳,236015 |
| |
| 摘 要： | 目的应用HPLC法测定乳酸依沙吖啶注射液的含量。方法高效液相色谱法。色谱柱为Kromasil C18柱（4.6 mm×250mm,5μm）;流动相为0.05%十二烷基磺酸钠-甲醇（30∶70）（磷酸调节pH3.3）;流速为1 ml·min^-1;检测波长370 nm。结果该方法在20.1～201.2 mg·L^-1的浓度范围内线性关系良好（r=0.999 9,n=6）,平均回收率为99.8%,RSD=0.9%（n=5）。结论方法快速准确,可用于乳酸依沙吖啶注射液的含量测定。
|
| 关 键 词： | 乳酸依沙吖啶 高效液相色谱 含量测定 |
| 修稿时间： | 2007-11-07 |
Determination of ethacridine lactate injection by HPLC |
| |
| LIU Yu-chun,LI Yan-na. Determination of ethacridine lactate injection by HPLC[J]. Anhui Medical and Pharmaceutical Journal, 2008, 12(3): 225-226 |
| |
| Authors: | LIU Yu-chun LI Yan-na |
| |
| Affiliation: | ( Fuyang Institute for Drug Control, Fuyang 236015, China ) |
| |
| Abstract: | Aim To establish an HPLC method for the determination of ethacridine lactate injection. Methods Kromasil C is （4.6 mm ～ 250 mm,5μm）column was used with the mobile phase consisting of 0.05 % sodium laurysulfonate and methanol（ 30： 70） adjusted to pH 3.3 by phosphoric acid and detected at wavelength 370 nm. Results The average recovery was 99.8% with RSD being 0.9% （ n = 5 ）. Conclusion The method is rapid, accurate, and sul.table for the determi.nation of ethacridine lactate injection. |
| |
| Keywords: | ethacridine lactate HPLC content determi.nation |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
