| 三维适形放疗同步化疗治疗局部晚期非小细胞肺癌效果 |
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| 引用本文： | 任群,余建和.三维适形放疗同步化疗治疗局部晚期非小细胞肺癌效果[J].齐鲁医学杂志,2010,25(1):10-12. |
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| 作者姓名： | 任群 余建和 |
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| 作者单位： | 兴化市人民医院放疗科,江苏,兴化,225700 |
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| 摘 要： | 目的探讨三维适形放疗联合多西他赛和顺铂同步化疗治疗不可手术的局部晚期非小细胞肺癌（NSCLC）的效果和毒副反应。方法将52例局部晚期NSCLC病人随机分为2组，各26例。单放组采用三维适形放疗，每日单次剂量DT2Gy，总剂量DT60-64Gy。化放组给予多西他赛30mg／m^2和顺铂20mg／m^2化疗，第1、8、22、29天分别在放疗前进行，放疗方法同单放组。结果化放组和单放组有效率分别为92．3％、76．9％，两组比较差异有显著性（χ^2=10．8，P〈0．05）。两组急性毒副反应发生率差异无显著性（P〉0．05）。结论三维适形放疗联合多西他赛和顺铂同步化疗治疗不可手术的局部晚期NSCLC的效果和病人耐受性较好。
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| 关 键 词： | 癌，非小细胞肺 放射疗法．适形 药物疗法 综合疗法 |
CLINICAL EFFECTS OF THREE DIMENSIONAL CONFORMAL RADIATION THERAPY COMBINED WITH CHEMOTHERAPY FOR PATIENTS WITH LOCALLY ADVANCED NON-SMALL CELL LUNG CANCER |
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| REN QUN,YU JIAN-HE.CLINICAL EFFECTS OF THREE DIMENSIONAL CONFORMAL RADIATION THERAPY COMBINED WITH CHEMOTHERAPY FOR PATIENTS WITH LOCALLY ADVANCED NON-SMALL CELL LUNG CANCER[J].Medical Journal of Qilu,2010,25(1):10-12. |
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| Authors: | REN QUN YU JIAN-HE |
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| Institution: | REN QUN,YU JIAN-HE(Department of Radiation Oncology,Xinghua First People\'s Hospital,Xinghua 225700,China) |
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| Abstract: | Objective To evaluate the effect and toxicity of three dimensional conformal radiation therapy(3DCRT) combined with chemotherapy using docetaxel and cisplatin for patients with unresected locally advanced non-small cell lung cancer(LA-NSCLC).Methods A total of 52 patients with LA-NSCLC were equally randomized to two groups.Those in radiotherapy group were given 3DCRT,2 Gy/single dose/day,totalling 60-64 Gy;those in the chemoradiotherapy group were administrated with docetaxel 30 mg/m2 and cisplatin 20 mg/m2... |
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| Keywords: | carcinoma non-small cell lung radiotherapy conformal drug therapy combined modality therapy |
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