2010-2015年兰州市围产儿出生缺陷及死亡率变化趋势

目的：分析2010—2015年兰州市围产儿出生缺陷、死亡状况及其变化趋势。方法收集兰州市2009年10月1日—2015年9月30日所有孕满28周至产后7天围产儿的资料。采用年估计百分比变化法（EAPC）评价围产儿出生缺陷发生率和围产儿死亡率的时间变化趋势。结果2010—2015年兰州市围产儿出生缺陷发生率城镇高于农村，全市和农村出生缺陷发生率均有上升趋势，其 EAPC 值分别为11.9％、14.1％；围产儿死亡病例以死胎为主，7天内围产儿死亡率逐年下降，EAPC 值为－15.9％。结论2010—2015年兰州市围产儿出生缺陷发生率呈上升趋势，城镇高于农村；围产儿死亡病例以死胎为主，7天内围产儿死亡率逐年下降。

Birth defects and mortality trends during the perinatal period in Lanzhou City,2010-2015

Objective To analyze trends of birth defects and deaths during the perinatal period in Lanzhou from 2010 to 2015. Methods Data on birth defects and deaths were analyzed by estimated annual percentage change. Results The rate of birth defects in urban area was higher than in rural area,with an upward tendency in the whole city and in the rural area,with an estimated annual percentage change of 11.9% and 14.1%,respectively.The main cause of deaths was stillborn.The mortality in 7 days of life decreased with an estimated annual percentage dange of -15.9%. Conclusion The reported rate of birth defects showed an increasing trend and the rate was higher in urban area than in rural area.In contrast,mortality in 7 days of life decreased with time.