| 妊娠肝内胆汁淤积症胎盘病理研究 |
| |
| 引用本文： | 肖建平,王海琦.妊娠肝内胆汁淤积症胎盘病理研究[J].医学综述,2006,12(7):409-411. |
| |
| 作者姓名： | 肖建平 王海琦 |
| |
| 作者单位： | 1. 南京医科大学附属无锡市妇幼保健院,江苏,无锡,214002
2. 南京医科大学附属第一临床医学院,南京,210029 |
| |
| 摘 要： | 妊娠合并肝内胆汁淤积症(ICP)是高危妊娠之一,可引起多种不良妊娠结局,多年来研究认为与高浓度胆盐沉积在胎盘绒毛板下致绒毛间隙狭窄、胎盘血流灌注不足,致胎儿宫内急、慢性缺氧相关。复习近几年来相关文献,综合ICP胎盘病理研究进展,试图从胎盘病理变化入手,阐述ICP时高浓度胆汁酸和胆红素的毒性作用及其致多种不良妊娠结局的机制。
|
| 关 键 词： | 妊娠 胆汁淤积 胎盘 病理 |
| 文章编号： | 1006-2084（2006）07-0409-03 |
| 收稿时间： | 2005-08-28 |
| 修稿时间： | 2006-03-20 |
Studies of the Placental Pathology in Intrahepatic Cholestasis of Pregnancy |
| |
| XIAO Jian-ping,WANG Hai-qi.Studies of the Placental Pathology in Intrahepatic Cholestasis of Pregnancy[J].Medical Recapitulate,2006,12(7):409-411. |
| |
| Authors: | XIAO Jian-ping WANG Hai-qi |
| |
| Institution: | 1. Wuxi Health Center for Women and Children Affiliated to Nanjing Medical University, Wuxi 214002, China ; 2. The First Clinical College of Najing Medical University, Najing 210029, China |
| |
| Abstract: | Intrahepatic cholestasis of pregnancy(ICP) is one of the high risk gestations,which can cause many kinds of poor pregnancy outcome.The final results studied for many years have shown that the poor outcome was related to acute and chronic hypoxia of fetal caused by intervillous lacuna stegnosis and placental hypoperfusion resulting from mineralization of high bile density.This article reviews the progress of study about placental pathology based on data in recent years in order to explain the toxic effect of high density in bile acid and bilirubin and its mechanism resulting in poor pregnancy outcome. |
| |
| Keywords: | Gravidity Intrahepatic cholestasis Placenta Pathology |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
