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结直肠癌的基因治疗
引用本文:郭贞,徐为.结直肠癌的基因治疗[J].医学综述,2009,15(2):216-219.
作者姓名:郭贞  徐为
作者单位:徐州医学院附属医院普外科,江苏徐州,221002
摘    要:结直肠癌是常见的消化道恶性肿瘤,目前治疗以外科手术为主,辅以放、化疗,术后5年生存率在50%左右。肿瘤基因治疗发展迅速,作为一种新的辅助治疗手段有重要意义。结直肠癌中研究比较多的是免疫基因治疗、自杀基因治疗、抑癌基因的应用等。基因疗法可以有效地杀伤肿瘤细胞,联合传统治疗方法可延长结直肠癌患者的生存时间,提高生活质量。

关 键 词:结直肠癌  基因治疗  基因

Gene Therapy of Colorectal Cancer
GUO Zhen,XU Wei.Gene Therapy of Colorectal Cancer[J].Medical Recapitulate,2009,15(2):216-219.
Authors:GUO Zhen  XU Wei
Institution:GUO Zhen,XU Wei. ( General Surgery Department,Affdiated Hospital of Xuzhou Medical College,Xuzhou 221002,China)
Abstract:Cotorectal cancer is a kind of malignant tumor of digestive canal with high incidence rate. The main treatment is surgery, combined with radiotherapy and chemotherapy. The survival rate is about 50% after surgery. Gene therapy is a useful adjunctive therapy,including immunogenic therapy," suicide" gene therapy, application of anti-oncogeue, and so on. It is efficient to kill tumor cell. When combined with traditional treatment, it can prolong live time of patients and improve life quality.
Keywords:Colorectal cancer  Gene therapy  Gene
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