| 天然高分子材料作为药物缓控释载体应用的研究进展 |
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| 引用本文： | 陈文平,江贵林,汪超,倪学文,李东生,姜发堂.天然高分子材料作为药物缓控释载体应用的研究进展[J].海峡药学,2009,21(11):5-9. |
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| 作者姓名： | 陈文平 江贵林 汪超 倪学文 李东生 姜发堂 |
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| 作者单位： | 1. 湖北工业大学生物工程学院,武汉,430068
2. 湖北工业大学生物工程学院,武汉,430068;武汉力诚生物科技有限公司,武汉,430068 |
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| 基金项目： | 湖北省教育厅，武汉市科技局晨光计划 |
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| 摘 要： | 由天然高分子材料构成的药物缓控释载体具有调节药物释放速率、稳定药物成分、提高生物利用率和帮助药物靶向定位等优点。本文简单介绍了胶原蛋白、纤维蛋白、纤维素、壳聚糖、海藻酸及海藻酸盐和魔芋葡甘聚糖作为药物缓控释载体的研究进展。
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| 关 键 词： | 天然高分子材料 缓控释放 载体 |
Advances in the application of biopolymer sustained/controlled release carriers |
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| CHEN Wen-ping,JIANG Gui-lin,WANG Chao,NI Xue-wen,LI Dong-sheng,JIANG Fa-tang.Advances in the application of biopolymer sustained/controlled release carriers[J].Strait Pharmaceutical Journal,2009,21(11):5-9. |
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| Authors: | CHEN Wen-ping JIANG Gui-lin WANG Chao NI Xue-wen LI Dong-sheng JIANG Fa-tang |
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| Institution: | CHEN Wen-ping, JIANG Gui-lin, WANG Chao, NI Xue-wen, LI Dong-sheng, JIANG Fa-tang(1. School of Biological Engineer., Hubei Univ. of Technology, Wuhan 430068, China; 2. Wuhan Licheng Biotechnology Co., Ltd., Wuhan 430068, China) |
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| Abstract: | The sustained/controlled carriers,which are combined with biopolymer,play the role in stabling drug components,sustaining/controlling release drug,improving drug bioavailability and aim-location.In this paper,advances in some biopolymers as sustained/controlled release carriers are introduced,including of collagen,fibrin,cellulose,chitosan,alginic acid and alginate,and KGM. |
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| Keywords: | Biopolymer Sustained/Controlled release Carriers |
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