| 血清新蝶呤及高敏C反应蛋白与动脉粥样硬化性脑梗死预后的相关性 |
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| 引用本文： | 吕艳,张毅,李东燕.血清新蝶呤及高敏C反应蛋白与动脉粥样硬化性脑梗死预后的相关性[J].兰州医学院学报,2008,34(3). |
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| 作者姓名： | 吕艳 张毅 李东燕 |
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| 作者单位： | 兰州大学第一临床医学院,甘肃,兰州,730000;甘肃省人民医院,神经内科,甘肃,兰州,730000 |
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| 摘 要： | 目的 探讨血清新喋呤及高敏C反应蛋白(HS-CRP)与动脉粥样硬化性脑梗死(ACl)病情严重程度及预后的关系.方法 采用酶联免疫吸附测定法测定57例ACI和29例腔隙性脑梗死(LI)患者发病24 h内、72 h、7d血清新蝶呤及HS-CRP水平,并与正常组32例体检者进行对照.结果 ACI组与LI组急性期血清新蝶呤及HS-CRP在发病24 h内升高,72 h达到最高,7 d时呈现下降趋势但仍高于正常;ACI组血清新蝶呤及HS-CRP高于LI组,LI组血清新蝶呤及HS-CRP高于正常对照组,差异有统计学意义(P<0.05);ACI组患者神经系统功能缺损程度评分与患者血清新蝶呤及HS-CRP水平呈正相关.结论 血清新蝶呤及HS-CRP呈动态变化趋势,提示ACI的发生是一个免疫炎症过程,可作为诊断和预后的指标.
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| 关 键 词： | 新喋呤 高敏C反应蛋白 动脉粥样硬化性脑梗死 |
Relationship between serum neoptrin as well as hypersensitive C reactive protein and the prognosis of atherosclerosis cerebral infarction |
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| L Yan,ZHANG Yi,LI Dong-yan.Relationship between serum neoptrin as well as hypersensitive C reactive protein and the prognosis of atherosclerosis cerebral infarction[J].Journal of Lanzhou Medical College,2008,34(3). |
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| Authors: | L Yan ZHANG Yi LI Dong-yan |
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| Institution: | L(U) Yan,ZHANG Yi,LI Dong-yan |
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| Abstract: | Objective To investigate the relationship between serum neoptrin as well as hypersen- sitive C reactive protein(HS-CRP) and the prognosis of atherosclerosis cerebral infarction(ACI). Methods Serum neoptrin and HS-CRP were detected in 57 cases of ACI and 29 cases of lacunar infarction(LI) by ELISA at 24 h,72 h,and 7 d respectively,and compared with 32 cases of normal physical examinees.Results In ACI and LI groups,serum neoptrin and HS-CRP presented an increased tendency within 24 h from onset,and reached th... |
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| Keywords: | neopterin hypersensitive C reactive protein atherosclerosis cerebral infarction |
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