3DCRT联合参芪扶正注射液治疗NSCLC有效性观察

目的 以胸部肿瘤中的非小细胞肺癌(NSCLC)为例,考察三维适形放射治疗(3DCRT)联合参芪扶正注射液治疗非小细胞肺癌(NSCLC)有效性。方法 将临床NSCLC拒绝手术或失去手术治疗时机的83例患者随机分配为对照组和试验组,对照组41例,试验组42例。对患者采取3DCRT联合参芪扶正注射液治疗,放疗标准为DT(60~70) Gy/(6~7)周,参芪扶正注射液每天给予静脉滴注剂量250 ml。评价两组患者的预后状况,包括近期疗效、消化道反应、骨髓抑制以及放射性肺炎的发生率。结果 全部病例病情缓解率为53%,其中对照组病情缓解率为51.2%,试验组病情缓解率54.8%;P> 0.05,对照组和试验组近期疗效无显著差异;骨髓抑制、消化道反应、放射性肺炎并发率对照组分别是3例占7.3%、5例占12.2%、9例占22%和2例占4.8%、4例占9.5%和7例占16.7%,试验组显著低于对照组,P< 0.05,差异有统计学意义。结论 3DCRT联合参芪扶正注射液治疗NSCLC有效,放疗毒性反应显著降低。

3DCRT Combined with Shenqi Fuzheng Injection Effectiveness Observation Treatment of NSCLC

Objective To thoracic tumors in non-small cell lung cancer,for example,investigated the three-dimensional conformal radiation therapy (3DCRT) combined with Shenqi Fuzheng Injection treatment of non-small cell lung cancer (NSCLC) effectiveness.Methods To clinical NSCLC refused surgery or lose the timing of surgical operation in treating 83 patients were randomly assigned into control group and experimental group,and control group 41 cases,42 cases of the test group. For patients to take 3DCRT combined with Shenqi Fuzheng Injection,radiotherapy standards DT(60~70) Gy/(6~7) weeks,Shenqi Fuzheng Injection 250ml intravenous infusion dose per day. Prognostic Assessment two groups of patients,including short-term effect,gastrointestinal reactions,bone marrow suppression,and the incidence of radiation pneumonitis.Results all cases the remission rate was 53%,which controls the remission rate was 51.2%,the experimental group remission rate was 54.8%;P>0.05,Control group and experimental group there was no significant difference in the near future curative effect,the bone marrow suppression,gastrointestinal tract reaction,radioactive pneumonia complicated with rate control group were 3 cases 7.3%,5 cases 12.2%,9 cases 22% and 2 cases 4.8%,4 cases 9.5% and 7 cases 16.7%,treatment group was significantly lower than the control group,P<0.05,with statistical significance.Conclusion 3DCRT combined with Shenqi Fuzheng Injection effective treatment of NSCLC,significantly reduces radiation toxicity.