Epidermodysplasia verruciformis associated with isolated IgM deficiency |
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Authors: | Gul Ulker Soylu Secil Yavuzer Rana |
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Institution: | Department of Dermatology, Ankara Numune Education and Research Hospital, Ankara, Turkey. |
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Abstract: | A 20 year-old man presented to our clinic with multiple warts on both hands and tumoral lesions on his face but otherwise healthy. On dermatological examination, numerous brown-black papular lesions, changing from 2 to 5 cm in diameter were found on his face along with multiple, flesh-coloured, flat-topped papules on the dorsa of his hands. A tumoral lesion, approximately 3 cm in diameter on the right side of his forehead and desquamated erythematous macules were also observed on the trunk. Laboratory investigations showed that serum immunoglobulin M (IgM) level was decreased. The histopathological examination of verrucous lesions on the hands was consistent with epidermodysplasia verruciformis and the histopathological diagnosis of the tumoral lesion was squamous cell carcinoma. |
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