重复经颅磁刺激治疗后循环短暂性脑缺血发作的疗效观察

目的探讨重复经颅磁刺激（rTMS）对后循环短暂性脑缺血发作患者血流速度的影响以及临床疗效观察。方法对132位后循环短暂性脑缺血发作受试者随机分入药物治疗组（分为对照组、阿司匹林组、丁洛地尔＋阿司匹林组）和高频rTMS联合药物（丁洛地尔＋阿司匹林）治疗组,并用经颅多普勒超声仪（TCD）观察其椎基底动脉脑血流速度在治疗前后的变化。结果患者入高频rTMS＋药物治疗组其rT-MS后椎基底动脉,收缩期峰值血流速度（peaksystolicvelocity,Vs）较药物治疗的3组增加明显（P〈0.05）,舒张末期血流速度（enddiastolicve-locity,Vd）较对照组、阿司匹林组药物治疗组增加（P〈0.05）比较丁洛地尔＋阿司匹林组差异无统计学意义,平均血流速度（mean velocity,Vm）较药物治疗的3组增加,刺激过程中无明显不适。结论 rTMS能增加后循环缺血患者的脑血流,改善症状,具有临床应用价值。

Efficacy of repetitive transcranial magnetic stimulation in treatment with transient ischemic attack of posterior circulation

Objective To observet the patients with transient ischemic attack of posterior circulation, using treatment of repetitive transcranial magnetic stimulation,to explore the clinic effect of this treatment. Methods A total of 132 patients conclusion detected by TCD, were randomly divided into four groups,drug therapy （control group,asplin group,asplin＋ Buflomedil group and drug therapy＋ rTMS group . Use TCD before and after treatment, analyze the hemodynamic change of Vertebral Artery and. Conclusions After Rtms with Vertebral artery insufficiency, the Vs of Vertebral artery of patients used rtms＋drug therapy were higher（P〈0.05 ） and the Vd were higher than the control group and asplin group（P〈0.05）,while no diffenrence to asplin＋ Buflomedil group .Vd of patients used rtms＋drug therapy were higher thanthe others. All patients felt no discomfort. Result rTMS treatment increase Vertebral Artery Blood flow, improve clinic syptoms, has clinic value.