一次婴儿毛细支气管肺炎爆发流行中病毒学和血清学观察

1985年12月至1986年2月江苏省泗洪县爆发流行小儿毛细支气管肺炎。12月份收住的例数占住院总例数的32%。发病最小年龄为28天,最大年龄为1岁半。6个月之内的占71.5%。从8份急性患儿的鼻咽洗液中分离出6株病毒,经鉴定为呼吸道合胞病毒。8例采得急性期和恢复期双份血清,恢复期中和抗体效价较急性期升高8~64倍。

Virologic and Serologic Observations in an Outbreak of Infantile Bronchiolopnemonitis

From December 1985 to February 1986 in Si Hong County, Jiang Su Province an outbreak of bronchopneumonitis occurred. In December the number of admitted infant cases with bronchopneumonitis was 32% of total hospitalized cases. The youngest infant was 28 days in age and the oldest was one and half years. 71.5% percent occurred in children less than six months in age. From nasopharyngeal washing of acute cases were isolated 6 strains of viruses. The result of identification of them revealed that they were respiratory syncytial virus. 3 pairs of serum sample were collected from acute and convalescent periods for neutralizing antibody titrations. The result showed that specific neutralizing antibody titers increased 8-64 fold in comparison between the acute and the convalescent.