| Ⅰ、Ⅱ相代谢酶基因多态性与前列腺癌发病风险 |
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| 引用本文： | 杨杰,钱立新. Ⅰ、Ⅱ相代谢酶基因多态性与前列腺癌发病风险[J]. 医学综述, 2006, 12(1): 10-12 |
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| 作者姓名： | 杨杰 钱立新 |
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| 作者单位： | 南京医科大学第一附属医院,南京,210029 |
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| 基金项目： | 国家重点基础研究发展计划(973计划) |
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| 摘 要： | 代谢酶基因多态性在人类恶性肿瘤发病中的作用已为越来越多的研究所证实,本文就近年来对Ⅰ、Ⅱ相代谢酶基因多态性和前列腺癌(PCa)发病风险之间关系的研究作简要综述,并着重讨论了多个基因多态性及基因与环境间交互作用对PCa发病的影响。
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| 关 键 词： | 基因多态性 代谢酶 前列腺癌 易感性 |
| 文章编号： | 1006-2084（2006）01-0010-03 |
| 收稿时间： | 2005-04-29 |
| 修稿时间： | 2005-10-09 |
Polymorphisms of Phase Ⅰ or Ⅱ Metabolic Enzyme Genes and Susceptibility to Prostate Cancer |
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| YANG Jie,QIAN Li-xin. Polymorphisms of Phase Ⅰ or Ⅱ Metabolic Enzyme Genes and Susceptibility to Prostate Cancer[J]. Medical Recapitulate, 2006, 12(1): 10-12 |
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| Authors: | YANG Jie QIAN Li-xin |
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| Affiliation: | Department of Urology, the First Hospital of Nanjing Medical University, Nanjing 210029, China |
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| Abstract: | At present,more and more researches have proved the important role of genotypic polymorphisms of phase Ⅰ or Ⅱ metabolic enzymes in tumor risk.This article reviews briefly the relationship between polymorphisms of Phase Ⅰ or Ⅱ enzyme genes and susceptibility to prostate cancer.Moreover,the interaction of genotype-environment in risk to prostate cancer is also discussed in the review. |
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| Keywords: | Genetic polymorphism Metabolic enzyme Prostate cancer Susceptibility |
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