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Supraorbital nerve conduction study in normal subjects
Authors:Therimadasamy Aravindakannan  Wilder-Smith Einar P  Lim Aymeric Y T  Yap Yan Lin  Yeo Matthew  Naidu Shenthilkumar  Lee Shu Jin
Affiliation:Neurology Diagnostic Laboratory, National University Hospital System, Singapore.
Abstract:There is currently no examination technique that allows direct measurement of supraorbital nerve conduction velocity and amplitude. Therefore, in this study we describe a novel nerve conduction technique that allows measurement of the supraorbital sensory nerve action potential (SNAP) distal to the supraorbital foramen. Supraorbital SNAPs were recorded bilaterally from 17 healthy volunteers using an antidromic technique. The SNAPs were consistently recordable over the site 6 cm lateral to the midline point that was marked 10 cm above the nasion. Measured parameters included peak latency (mean 2.3 ms, SD 0.3), amplitude (mean 14.6 μV; SD 10.5), and velocity (mean 51.3 m/s, SD 6.8). The mean percentage of interside difference in amplitude was 25.6% (SD 17.3). Cut-off values (97th percentile) were 2.7 ms (peak latency), 3.3 μV (amplitude), 41.9 m/s (conduction velocity), and 54.9% (interside difference in amplitude). Supraorbital SNAPs can be recorded in all normal subjects and used as a quantitative measure of the functioning large fibers in the nerve.
Keywords:nerve conduction  sensory nerve action potential  supraorbital nerve  supraorbital neuralgia  trigeminal nerve
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