高血压并缺血性脑卒中患者经颅多普勒脑血流动力学变化的研究

目的 探讨高血压并缺血性脑卒中患者血压、年龄对脑血流变化的影响。方法 对经头颅CT确诊的258例缺血性脑卒中住院患者，分为高血压组和正常血压组，高血压组又分为老年组和非老年组，采用经颅多普勒（TCD）超声诊断仪探测双侧大脑中动脉（MCA）、大脑前动脉（ACA）、大脑后动脉（PCA），记录平均血流速度（Vm）、血管搏动指数（PI）、阻力指数（RI）。结果 高血压老年组与高血压非老年组比较，老年组双侧ACA、MCA、PCA的Vm均较非老年组减低（P〈0．05），而PI及RI较非老年组显著增高（P〈0．01）；正常血压组与高血压组比较，两组Vm、PI及砌无显著性差异（P〉0．05）。结论 高血压并缺血性脑卒中后，血压对脑血流量的影响不明显，年龄是影响脑血流量的主要因素。

Investigation of haemodynamics by transcranial Doppler in patients with essential hypertension complicating with ischemic stroke

Objective To investigate the effects of blood pressure and age on the change of cerebral blood flow in the patients with essential hypertension complicating with ischemic stroke.Methods 258 hospitalization patients with ischemic stroke diagnosed by transcranial CT were divided into hypertension group and normal blood pressure group,hypertension group was subgrouped into old group and non-old group.Middle cerebral artery(MCA),anterior cerebral artery(ACA)and posterior cerebral artery(PCA)were detected by transcranial Doppler to record the average blood flow rate(Vm),blood vessel pulsatility index(PI) and resistance index(RI).Results Vm in ACA,MCA and QCA in old group were lower than those in non-old group(P<0.05),but PI and RI were higher in old group than those in non-old group(P<0.01).There was no significant difference in Vm, PI and RI between hypertension group and normal blood pressure group(P>0.05).Conclusions Age was the main influential factor of the cerebral blood blow in hypertension with ischemic stroke but blood pressure was not.