泌尿系感染病原菌的分布及耐药性分析

目的探讨本地区引起泌尿系感染的病原菌及其耐药性,为临床治疗提供依据。方法用常规方法分离鉴定病原菌,用K-B法进行药物敏感试验。结果302株病原菌中革兰阴性杆菌252株,占83%,主要为大肠埃希菌和肺炎克雷伯菌。革兰阳性球菌38株,占13%。真菌12株,占4%。大肠埃希菌产ESBLs检出率为43.8%,肺炎克雷伯菌产ESBLs检出率为57.1%,耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)的检出率为56.2%,MRSA的检出率为22.2%。结论了解引起泌尿系感染病原菌的分布及耐药性监测,合理使用抗菌药物以减少耐药菌株的产生和医院感染的爆发流行。

Pathogen distribution and resistance in urinary tract infections

Objective To explore the distribution and antibiotic resistance of pathogens in urinary tract infections. Methods Bacterial susceptibility testing was carried out using Kirby-Bauer disk method. Results A total of 302 clinical isolates including 252 (83%) strains of gram-negative bacilli, mainly Escherichia coli and Klebsiella pneumoniae, 38 (13%) strains of gram-positive cocci, and 12 (4%) strains of fungi were collected. About 43.8% of the E. coli isolates and 57.1% of the Klebsiella pneumoniae isolates produced ESBLs. The prevalence of methicillin-resistant coagulase-negative Staphylococcus (MRCNS) was 56.2%. The prevalence of MRSA was 22.2%. Conclusions It is important to understand the distribution and resistant pattern of pathogens causing urinary tract infections for effectively controlling nosocomial outbreak infections and reducing the emergence of resistant pathogens.